143R-1

CD43 (SP55) Rabbit Monoclonal Antibody

• Kod UNSPSC: 12352203
• NACRES: NA.41
• klon: SP55, monoclonal
• application: IHC (p)
• reaktywność gatunkowa: human
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• citations: 2

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 500
• białko sprzężone: unconjugated
• forma przeciwciała: culture supernatant
• rodzaj przeciwciała: primary antibodies
• klon: SP55, monoclonal
• opis: For In Vitro Diagnostic Use in Select Regions (See Chart)
• Formularz: buffered aqueous solution
• reaktywność gatunkowa: human
• opakowanie: vial of 0.1 mL concentrate (143R-14); vial of 0.5 mL concentrate (143R-15); bottle of 1.0 mL predilute (143R-17); vial of 1.0 mL concentrate (143R-16); bottle of 7.0 mL predilute (143R-18)
• metody: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:100-1:500
• izotyp: IgG1
• kontrola: tonsil
• Warunki transportu: wet ice
• temp. przechowywania: 2-8°C
• wizualizacja: membranous
• informacje o genach: human ... SPN(6693)

Opis

Opis ogólny

CD43, also called leukosialin, is expressed on the surface of all leukocytes except for some resting B-cells. It appears to function as an anti-adhesion molecule, mediating repulsion amongst leukocytes. CD43 expression in lymphomas is highly correlated with CD5; thus most T-cell malignancies and a group of small lymphocyte B-cell malignancies [CLL/ SLL, mantle cell lymphoma (MCL), prolymphocytic leukemia] are often positive, while follicular lymphoma (FL) is usually negative. Anti-CD43 is less useful as a lineage marker, but is a sensitive indicator of aberrant B-cell populations. From 70 to 90% of T-cell lymphomas are labeled with this antibody. Plasmacytoma/myeloma and mast cell disease are also labeled with this antibody. No reactivity has been observed with reactive B-cells.

Jakość

IVD

IVD

IVD

RUO

Powiązanie

CD43 Positive Control Slides, Product No. 143S, are available for immunohistochemistry (formalin-fixed, paraffin-embedded sections).

Postać fizyczna

Solution in Tris Buffer, pH 7.3-7.7, with 1% BSA and <0.1% Sodium Azide

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable