MABT37

Anti-Dentin sialoprotein Antibody, clone 2C12.3

clone 2C12.3, from mouse

• Synonim(y): Dentin sialophosphoprotein, Dentin phosphoprotein, Dentin phosphophoryn, DPP2.Dentin sialoprotein, DSP
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: 2C12.3, monoclonal
• reaktywność gatunkowa: mouse, rat
• metody: immunohistochemistry: suitable
• izotyp: IgG2bκ
• numer dostępu NCBI: NP_036922
• numer dostępu UniProt: Q62598
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: mouse ... Dspp(666279)

Opis

Opis ogólny

Dentin sialophosphoprotein (DSPP) is a protein of the extracellular matrix. It belongs to the small integrin-binding ligand, N-linked glycoprotein (SIBLING) family. DSPP is found in teeth and bone and is primarily involved in biomineralization processes in these structures. This function may be facilitated by the interaction of DSPP with multiple protein targets including DMP1, BMP2, Runx2, and NF-Y. DSPP plays a central role in dentinogenesis.

Immunogen

Pure DSP isolated rat dentin

Zastosowanie

Anti-Dentin sialoprotein, clone 2C12.3 detects levels of Dentin sialoprotein proteins & has been published & validated for use in IHC.

Immunohistochemistry Analysis: A representative lot was used by an independent laboratory in rat mandibular tissue. (Baba, O., et al. (2004). Eur J Oral Sci. 112:163–170.)

Research Category
Cell Structure

Research Sub Category
Cytoskeleton

Jakość

Evaluated by Immunohistochemistry in mouse and rat teeth tissues.

Immunohistochemistry Analysis: 1:250-1,000 dilution of this antibody detected Dentin sialophosphoprotein in mouse and rat teeth tissues.

Opis wartości docelowych

68 kDa calculated. Uniprot describes 2 isoforms at 64 and 70 kDa

Postać fizyczna

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2bκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
Mouse and rat teeth tissues

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable