MABC39

Anti-LAMP-1 (CD107a) Antibody, clone 1D4B

clone 1D4B, from rat

• Synonim(y): lysosomal-associated membrane protein 1, lysosome-associated membrane glycoprotein 1, Lysosome-associated membrane protein 1, CD107 antigen-like family member A, CD107a antigen
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rat
• Poziom jakości: 100
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: 1D4B, monoclonal
• reaktywność gatunkowa: mouse
• metody: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• izotyp: IgG2aκ
• numer dostępu NCBI: NP_034814
• numer dostępu UniProt: P11438
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: mouse ... Lamp1(16783)

Opis

Opis ogólny

Lysosome-associated membrane protein 1 (LAMP-1) is a highly glycosolated, single-pass type 1 membrane protein belonging to the lysosome- associated membrane protein family; a group of proteins that make up the majority of the lysosomal membrane and are considered crucial mediators for cellular adhesion by interacting with carbohydrate receptors. LAMP-1 functions to traffic carbohydrate ligands to selectins. It is also thought to play a role in tumor cell metastasis.

Immunogen

NIH/3T3 plasma membrane fraction of mouse LAMP-1.

Zastosowanie

Detect LAMP-1 (CD107a) using this Anti-LAMP-1 (CD107a) Antibody, clone 1D4B validated for use in WB, IP, IC, IH, FC.

Immunoprecipitation Analysis: A previous lot was used by an independent laboratory in IP (Chen, 1985).

Immunocytochemistry Analysis: A previous lot was used by an independent laboratory in IC (Chen, 1985).

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Tumor Markers

Jakość

Evaluated by Western Blot in NIH/3T3 cell lysate.

Western Blot Analysis: 1:50,000 dilution of this antibody detected LAMP-1 in 10 µg of NIH/3T3 cell lysate.

Opis wartości docelowych

~ 100 kDa observed. The calculated molecular weight of this protein is 44 kDa The protein is heavily glycosolated and therefore its molecular weight is typically noted from 95-115 kDa

Postać fizyczna

Format: Purified

Protein G

Purified rat monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
NIH/3T3 cell lysate

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable