MABC151

Anti-Hyaluronan synthase 2 Antibody, clone 2B11.1

clone 2B11.1, from mouse

• Synonim(y): Hyaluronan synthase 2, Hyaluronate synthase 2, Hyaluronic acid synthase 2, HA synthase 2
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified antibody
• rodzaj przeciwciała: primary antibodies
• klon: 2B11.1, monoclonal
• reaktywność gatunkowa: human
• metody: immunohistochemistry: suitable (paraffin); western blot: suitable
• izotyp: IgG2aκ
• numer dostępu NCBI: NP_005319
• numer dostępu UniProt: Q92819
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... HAS2(3037)

Opis

Opis ogólny

Hyaluronan synthase 2 (HAS2) is also known as Hyaluronate synthase 2, or Hyaluronic acid (HA) synthase 2. As the name suggests, HAS2 is involved in hyaluronan/hyaluronic acid synthesis. Hyaluronan synthase 2 is expressed in fibroblasts. Chromosomal aberrations involving Hyaluronan synthase 2 may be a cause of lipoblastomas, usually diagnosed in children.

Specyficzność

This antibody recognizes the cytoplasmic domain of Hyaluronan synthase 2.

Immunogen

Epitope: Cytoplasmic domain

GST-tagged recombinant protein corresponding to the cytoplasmic domain of human Hyaluronan synthase 2.

Zastosowanie

Detect Hyaluronan synthase 2 using this mouse monoclonal antibody, Anti-Hyaluronan synthase 2 Antibody, clone 2B11.1 validated for use in western blotting & IHC (Paraffin).

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Western Blotting Analysis: 2.0 µg/mL from a representative lot detected Hyaluronan synthase 2 in 10 µg of K562 cell lysate.
Immunohistochemistry Analysis: A 1:250 dilution from a representative lot detected Hyaluronan synthase 2 in human breast adenocarcinoma cell tissue.

Jakość

Evaluated by Western Blotting in MRC-5 cell lysate.

Western Blotting Analysis: 0.2 µg/mL of this antibody detected Hyaluronan synthase 2 in 200 µg of MRC-5 cell lysate.

Opis wartości docelowych

~ 64 kDa observed

Postać fizyczna

Format: Purified

Protein G Purified

Purified mouse monoclonal IgG2aκ in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
MRC-5 cell lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable