MAB3070
Anti-Granzyme B Antibody, clone GrB-7
culture supernatant, clone GrB-7, Chemicon®
Synonim(y):
Anti-Anti-CSP-B, Anti-Anti-HLP, Anty-C11, Anty-CCPI, Anty-CGL-1, Anty-CGL1, Anty-CSPB, Anty-CTLA1, Anty-CTSGL1, Anty-SECT
Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych
About This Item
Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41
Polecane produkty
pochodzenie biologiczne
mouse
Poziom jakości
forma przeciwciała
culture supernatant
rodzaj przeciwciała
primary antibodies
klon
GrB-7, monoclonal
reaktywność gatunkowa
human
producent / nazwa handlowa
Chemicon®
metody
immunohistochemistry: suitable (paraffin)
western blot: suitable
izotyp
IgG2a
numer dostępu NCBI
numer dostępu UniProt
Warunki transportu
dry ice
docelowa modyfikacja potranslacyjna
unmodified
informacje o genach
human ... GZMB(3002)
Specyficzność
Monoclonal antibody recognizes the 33 kDa granzyme B.
Reacts specifically with human serine protease granzyme B. Does not cross-react with human granzyme A. Granzyme B localizes in cytoplasmic granules and can be used as a marker for NK cells and activated cytotoxic T-cells.
Reacts specifically with human serine protease granzyme B. Does not cross-react with human granzyme A. Granzyme B localizes in cytoplasmic granules and can be used as a marker for NK cells and activated cytotoxic T-cells.
Zastosowanie
Detect Granzyme B using this Anti-Granzyme B Antibody, clone GrB-7 validated for use in WB, IH(P).
Immunoblotting
Immunohistochemistry of granzyme B-expressing lymphocytes in sublimate sections and formalin-fixed paraffin-embedded tissues (1:20 dilution). Does not react with other cell types. Cannot be used on frozen sections.
Note on the use of MAB3070 on paraffin sections:
Tissue slides should be pretreated with an antigen retrieval method, such as treatment with 0.1M sodium citrate for 10 min at 100°C. A working dilution of 1:20 is advised, but optimal working dilutions must be determined by end user.
Immunohistochemistry of granzyme B-expressing lymphocytes in sublimate sections and formalin-fixed paraffin-embedded tissues (1:20 dilution). Does not react with other cell types. Cannot be used on frozen sections.
Note on the use of MAB3070 on paraffin sections:
Tissue slides should be pretreated with an antigen retrieval method, such as treatment with 0.1M sodium citrate for 10 min at 100°C. A working dilution of 1:20 is advised, but optimal working dilutions must be determined by end user.
Research Category
Apoptosis & Cancer
Metabolism
Apoptosis & Cancer
Metabolism
Research Sub Category
Apoptosis - Additional
Enzymes & Biochemistry
Apoptosis - Additional
Enzymes & Biochemistry
Postać fizyczna
Liquid
Przechowywanie i stabilność
Maintain at -20°C for up to 12 months.
Informacje prawne
CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany
Oświadczenie o zrzeczeniu się odpowiedzialności
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania
10 - Combustible liquids
Klasa zagrożenia wodnego (WGK)
WGK 2
Certyfikaty analizy (CoA)
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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.
T F Barth et al.
Virchows Archiv : an international journal of pathology, 436(4), 357-364 (2000-06-02)
In contrast to primary gastric lymphomas of B-cell type, little is known about primary gastric T-cell lymphomas. We describe three cases with remarkably similar features: diffuse growth, epitheliotropism, medium too large cell size, high apoptotic rates, and a CD3+, CD4+
Milan Fiala et al.
Journal of neuroinflammation, 7, 76-76 (2010-11-11)
The contribution of inflammation to neurodegenerative diseases is increasingly recognized, but the role of inflammation in sporadic amyotrophic lateral sclerosis (sALS) is not well understood and no animal model is available. We used enzyme-linked immunosorbent assays (ELISAs) to measure the
Functional dissociation between proforms and mature forms of proteinase 3, azurocidin, and granzyme B in regulation of granulopoiesis.
Stefan Skold, Lennart Zeberg, Urban Gullberg, Tor Olofsson
Experimental Hematology null
Regulatory, effector, and cytotoxic T cell profiles in long-term kidney transplant patients.
Joanna Ashton-Chess,Emilie Dugast,Robert B Colvin,Magali Giral,Yohann Foucher,Anne Moreau et al.
Journal of the American Society of Nephrology null
P C de Bruin et al.
Blood, 84(11), 3785-3791 (1994-12-01)
T-cell non-Hodgkin's lymphomas can be considered the neoplastic equivalents of immunologically functional, site-restricted T lymphocytes. Little is known about the occurrence and clinical behavior of T-cell lymphomas that are the neoplastic equivalents of different functional T-cell subsets. Here, we investigated
Nasz zespół naukowców ma doświadczenie we wszystkich obszarach badań, w tym w naukach przyrodniczych, materiałoznawstwie, syntezie chemicznej, chromatografii, analityce i wielu innych dziedzinach.
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