MAB2642

Anti-Fibrillin-2 Antibody, clone 48

clone 48, from mouse

• Synonim(y): fibrillin 2, congenital contractural arachnodactyly, Fibrillin 5
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• forma przeciwciała: purified antibody
• rodzaj przeciwciała: primary antibodies
• klon: 48, monoclonal
• reaktywność gatunkowa: human
• metody: ELISA: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_001990
• numer dostępu UniProt: P35556
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... FBN2(2201)

Opis

Opis ogólny

Fibrillin-2 is a part of the Fibrillin family of glycoproteins, which are essential factors in the formation and maintenance of elastic fibers known as microfibrils within the extracellular matrix. Various researchers have suggested that Fibrillin-2 has a role in the mediation of microfibril assembly during early elastogenesis. Defects in Fibrillin-2 are causal to a rare disorder involving autosomal dominant connective tissue known as congenital contractual arachnodactyly (CCA), also known as Beals syndrome or distal arthrogryposis type 9 (DA9), and is similar to Marfan syndrome.

Specyficzność

The antibody recognizes Fibrillin-2.

Immunogen

Recombinant protein corresponding to human Fibrillin-2.

Zastosowanie

Anti-Fibrillin-2 Antibody, clone 48 is an antibody against Fibrillin-2 for use in IH, ELISA, IP & IC.

ELISA Analysis: A previous lot was used by an independent laboratory in ELISA (Charbonneau, 2003).

Immunofluorescence Analysis: A previous lot was used by an independent laboratory in IF (Charbonneau, 2003).

Jakość

Evaluated by Immunohistochemistry in liver cancer and papillary serous carcinoma paraffin-embedded tissue sections.

Immunohistochemistry Analysis: 1:50 dilution of this antibody detected Fibrillin-2 in paraffin-embedded tissue sections of liver cancer and papillary serous carcinoma.

Opis wartości docelowych

~ 215 kDa

Postać fizyczna

Format: Purified

Komentarz do analizy

Control
Liver cancer and papillary serous carcinoma tissue

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable