FCMAB269F

Milli-Mark^® Anti-Integrin β1 (CD29)-FITC conjugate Antibody, clone MB1.2

clone MB1.2, Milli-Mark^®, from rat

• Synonim(y): CD29 antigen, Fibronectin receptor subunit beta, Integrin VLA-4 subunit beta, fibronectin receptor beta subunit, integrin VLA-4 beta subunit, integrin beta 1, integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rat
• Poziom jakości: 100
• białko sprzężone: FITC conjugate
• forma przeciwciała: purified antibody
• rodzaj przeciwciała: primary antibodies
• klon: MB1.2, monoclonal
• reaktywność gatunkowa: mouse
• producent / nazwa handlowa: Milli-Mark^®
• metody: flow cytometry: suitable
• izotyp: IgG2aκ
• numer dostępu NCBI: NP_002202
• numer dostępu UniProt: P05556
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... ITGB1(3688)

Opis

Opis ogólny

Integrin beta 1, also known as CD29, is a 130 kDa transmembrane glycoprotein that forms noncovalent complexes with various Integrin alpha subunits (including alpha 1, alpha 2, alpha 3, alpha 4, alpha 5, and alpha 6, also known as CD49a, CD49b, CD49c, CD49d, CD49e, and CD49f, respectively) to form the functional receptors that bind to specific extracellular matrix proteins. Integrin receptors are involved in the regulation of a variety of important biological functions, including embryonic development, wound repair, hemostasis, and prevention of programmed cell death. They are also implicated in abnormal pathological states such as tumor directed angiogenesis, tumor cell growth, and metastasis. Interactions between integrins and the extracellular matrix lead to activation of signal transduction pathways and regulation of gene expression.

Specyficzność

Antibody recognizes integrin β1.

Zastosowanie

Research Category
Cell Structure

Research Sub Category
Integrins

This Milli-Mark Anti-Integrin β1 (CD29)-FITC conjugate Antibody, clone MB1.2 is validated for use in FC for the detection of Integrin β1 (CD29) conjugate.

Jakość

Evaluated by flow cytometry using NIH/3T3

Opis wartości docelowych

88 kDa Calculated

Postać fizyczna

Protein A purified

Purified rat monoclonal IgG2a conjugated to FITC in PBS with 0.1% sodium azide and 15 mg/mL BSA.

Przechowywanie i stabilność

Maintain refrigerated at 2-8°C protected from light for up to 6 months from date of receipt.

Komentarz do analizy

Control
NIH/3T3 cells

Informacje prawne

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable