FCMAB188F

Milli-Mark^® Anti-CD24-FITC Antibody, clone SN3

clone SN3, Milli-Mark^®, from mouse

• Synonim(y): Signal transducer CD24, Small cell lung carcinoma cluster 4 antigen
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.44

Właściwości

• pochodzenie biologiczne: mouse
• Poziom jakości: 100
• białko sprzężone: FITC conjugate
• forma przeciwciała: purified immunoglobulin
• rodzaj przeciwciała: primary antibodies
• klon: SN3, monoclonal
• reaktywność gatunkowa: human
• producent / nazwa handlowa: Milli-Mark^®
• metody: flow cytometry: suitable
• izotyp: IgG1κ
• numer dostępu NCBI: NP_037362.1
• numer dostępu UniProt: P25063
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... CD24(100133941)

Opis

Opis ogólny

The CD24 antigen, which has a molecular weight of 35-45 kDa, is a glycosyl phosphatidylinositol (GPI)-anchored surface molecule. It is a member of a family that also includes HSA and CD52. Cross-linking of CD24 can induce increased intracellular Ca++ in mature B lymphocytes (Turni, 2002).
CD24 is expressed at multiple stages of B cell development, beginning with the bone marrow CD34+ pro-B-cell compartment and continuing through mature surface IgM+/IgD+ B cells. Plasma cells express very low to negligible levels of CD24 (Le Bien, 1995). CD24 is not expressed on the cell surface of normal T cells or monocytes, but is expressed on mature granulocytes (Le Bien, 1995; Fukukawa, 1986). The antigen is also present on a variety of epithelial types (Turni, 2002).

Specyficzność

Antibody recognizes Human CD24 antigen.

Immunogen

Isolated membrane fraction of the pre-B leukemic cell line NALM-1.

Zastosowanie

Detect CD24 using this Milli-Mark Anti-CD24-FITC Antibody, clone SN3 validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Jakość

Evaluated by flow cytometry using human PBMCs

Opis wartości docelowych

35-45 kDa (Turni, 2002)

Postać fizyczna

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Przechowywanie i stabilność

Maintained refrigerated at 2-8°C from date of receipt. Protected from light in undiluted aliquots for 6 months from date of receipt.

Komentarz do analizy

Control
PBMCs

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informacje prawne

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable