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Merck
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Kluczowe dokumenty

AG714

Sigma-Aldrich

Human IgG, Fc Fragment

Synonim(y):

Fragment Fc IgG

Zaloguj sięWyświetlanie cen organizacyjnych i kontraktowych


About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

human

Poziom jakości

forma przeciwciała

purified immunoglobulin

producent / nazwa handlowa

Chemicon®

Warunki transportu

wet ice

docelowa modyfikacja potranslacyjna

unmodified

Opis ogólny

Product Source: Human serum. Tested by an FDA approved test method and found negative for HIV antibody, Hepatitis B Surface Antigen, antibody to Hepatitis C and syphilis.

Zastosowanie

Research Category
Controls

Postać fizyczna

Format: Purified
Sterile liquid in 0.01 M Sodium Phosphate, 0.25 M NaCl, pH 7.6. No preservatives have been added.

Przechowywanie i stabilność

Store under sterile conditions at +2-8°C for up to one year. Dilute only as needed for a single day′s use.

Komentarz do analizy

Single precipitin line by immunoelectrophoresis at 20 mg/mL against Goat anti-Human whole serum. No cross-reactivity against Goat anti-Human IgG F(ab′)2 fragment, IgM, Fc(5μ) or IgA, alpha-chain specific. Purified by column chromatography.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

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Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Iftiin Hassan Mohamed et al.
Pharmacological research, 64(5), 464-470 (2011-07-12)
The Eph tyrosine kinase receptors and their ephrin ligands play a central role in several human cancers and their deregulated expression or function promotes tumorigenesis, inducing aggressive tumor phenotypes. Green tea extracts (GTE) have been recently found to inhibit Eph-kinase
Sara C Humphreys et al.
Drug metabolism and disposition: the biological fate of chemicals, 47(10), 1174-1182 (2019-05-18)
Understanding small interfering RNA (siRNA) fraction unbound (f u) in relevant physiologic compartments is critical for establishing pharmacokinetic-pharmacodynamic relationships for this emerging modality. In our attempts to isolate the equilibrium free fraction of N-acetylgalactosamine-conjugated siRNA using classic small-molecule in vitro
Anabel Gonzalez-Gil et al.
The Journal of allergy and clinical immunology, 147(4), 1442-1452 (2020-08-14)
The immunoinhibitory receptor Siglec-8 on the surface of human eosinophils and mast cells binds to sialic acid-containing ligands in the local milieu, resulting in eosinophil apoptosis, inhibition of mast cell degranulation, and suppression of inflammation. Siglec-8 ligands were found on
Christian Henneberger et al.
Neuron, 108(5), 919-936 (2020-09-26)
Extrasynaptic actions of glutamate are limited by high-affinity transporters expressed by perisynaptic astroglial processes (PAPs): this helps maintain point-to-point transmission in excitatory circuits. Memory formation in the brain is associated with synaptic remodeling, but how this affects PAPs and therefore
Massimiliano Tognolini et al.
ChemMedChem, 7(6), 1071-1083 (2012-04-25)
The Eph-ephrin system, including the EphA2 receptor and the ephrinA1 ligand, plays a critical role in tumor and vascular functions during carcinogenesis. We previously identified (3α,5β)-3-hydroxycholan-24-oic acid (lithocholic acid) as an Eph-ephrin antagonist that is able to inhibit EphA2 receptor

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