ABT338

Anti-EBI3 Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): Interleukin-27 subunit beta, IL-27 subunit beta, IL-27B, Epstein-Barr virus-induced gene 3 protein, EBV-induced gene 3 protein
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: human
• metody: immunofluorescence: suitable; immunohistochemistry: suitable; western blot: suitable
• numer dostępu UniProt: Q14213
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... EBI3(10148)

Opis

Opis ogólny

Epstein-Barr virus-induced gene 3 protein (EBI3), also known as Interleukin-27 subunit beta (IL27B), is a member of the type I cytokine receptor family (Type 3 subfamily) that is composed of two subunits: interleukin-27 (IL-27) and IL-35. EBI3 regulates T-helper cell development, stimulates cytotoxic T-cell activity, suppresses T-cell proliferation, and induces isotype switching in B-cells. EBI3 also plays an important role in its antitumor activity as well as its antiangiogenic activity.

Specyficzność

This antibody recognizes the C-terminus of EBI3.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human EBI3.

Zastosowanie

Detect IL-27 using this rabbit polyclonal antibody, Anti-EBI3 Antibody validated for use in western blotting, IHC & Immunofluorescence.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected EBI3 in human spleen tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected EBI3 in human spleen cells.

Research Category
Cell Structure

Research Sub Category
Cytokines & Cytokine Receptors

Jakość

Evaluated by Western Blotting/Peptide Inhibition Assay in K562 cell lysate.

Western Blotting/Peptide Inhibition Assay Analysis: 1 µg/mL of this antibody detected EBI3 in 15 µg of K562 cell lysate.

Opis wartości docelowych

~37 kDa observed. Uncharacterized bands may appear in some lysate(s).

Postać fizyczna

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
K562 cell lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable