ABT334

Anti-TSLP receptor Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): TSLP Receptor Antibody, TSLP Receptor, Thymic stromal lymphopoietin receptor, CRL2, ILXR, TSLPR, Cytokine receptor-like factor 2, Cytokine receptor-like 2, IL-XR
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: human
• metody: immunofluorescence: suitable; immunohistochemistry: suitable (paraffin); western blot: suitable
• numer dostępu UniProt: Q9HC73
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... TSLP(85480)

Opis

Opis ogólny

Thymic stromal lymphopoietin (TSLP) receptor is a member of the Type I cytokine receptor family (type 5 subfamily). TSLP has been shown to play an important role in dendritic cell maturation and activation. Additionally, TSLP receptor is involved in the positive selection of regulatory T cells, induction of CD4+ T cell-mediated allergic reaction and maintenance of peripheral CD4+ T cell homeostasis. Furthermore, TSLP receptor is implicated in the development of the hematopoietic system. TSLP receptor forms a functional complex with TSLP receptor and IL7R which is capable of stimulating cell proliferation through activation of STAT3 and STAT5. TSLP receptor is primarily expressed in dendrites and monocytes. Additionally, it is expressed in heart, skeletal muscle, kidney and adult and fetal liver; and weakly expressed in T-cells.

Immunogen

KLH-conjugated linear peptide corresponding to human TSLP receptor.

Zastosowanie

Detect TLSP Receptor using this rabbit polyclonal antibody, Anti-TSLP receptor Antibody validated for use in western blotting, IHC (Paraffin) & Immunofluorescence.

Immunohistochemistry Analysis: 5 µg/mL from a representative lot detected TSLP receptor in human liver tissue.

Immunofluorescence Analysis: 20 μg/mL from a representative lot detected TSLP receptor in human liver cells.

Research Category
Signaling

Research Sub Category
Cytokines & Cytokine Receptors

Jakość

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected TSLP receptor in 15 µg of human liver tissue lysate.

Opis wartości docelowych

~53 kDa observed. Uncharacterized bands may appear in some lysate(s). Uniprot describes 2 isoforms at ~27 kDa and ~42 kDa

Postać fizyczna

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Przechowywanie i stabilność

Stable for 1 year at 2-8°C from date of receipt.

Komentarz do analizy

Control
Human liver tissue lysate

Inne uwagi

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable