ABN58

Anti-phospho MAP1B (Thr1265) Antibody

from rabbit, purified by affinity chromatography

• Synonim(y): Microtubule-associated protein 1B, MAP-1B, MAP1(X), MAP1.2, MAP1 light chain LC1
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa: rat
• reaktywność gatunkowa (przewidywana na podstawie homologii): mouse (immunogen homology)
• metody: immunocytochemistry: suitable; immunohistochemistry: suitable; western blot: suitable
• numer dostępu UniProt: P14873
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: phosphorylation (pThr1265)
• informacje o genach: mouse ... Map1B(17755) ; rat ... Map1B(29456)

Opis

Opis ogólny

Microtubule-associated protein 1B (MAP1B) is neuron-specific and is thought to play a part in controlling the neuronal cytoskeleton. MAP1B is made up of heavy and light chains and is involved in the microtubule and actin filament association. MAP1B may have an important role in axon formation by supporting microtubule dynamics and controlling cytoskeletal arrangement. MAP1B has also been associated with Netrin 1 signaling.

Specyficzność

Other homologies: Human (91% sequence homology).

This antibody recognizes MAP1B phosphorylated at Thr1265.

Immunogen

Epitope: Phosphorylated Thr1265

KLH-conjugated linear peptide corresponding to mouse MAP1B phosphorylated at Thr1265.

Zastosowanie

Anti-phospho MAP1B (Thr1265) Antibody is an antibody against phospho MAP1B (Thr1265) for use in WB, IH & IC.

Immunohistochemistry Analysis: 1:600 dilution from a representative lot detected MAP1B in embryonic (E12) rat spinal cord tissue. (Image courtesy of Dr. Phillip R. Gordon-Weeks, King′s College London.)

Immunofluorescence Analysis: A representative lot was used by an independent laboratory in IF. (Trivedi, N., et al. (2005). Journal of Cell Science. 118:993-1005.)

Jakość

Evaluated by Western Blot in S1 rat brain tissue lysate.

Western Blot Analysis: 1:1,000 dilution of this antibody detected MAP1B on 10 µg of S1 rat brain tissue lysate.

Opis wartości docelowych

~300 kDa observed

Komentarz do analizy

Control
S1 rat brain tissue lysate

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 10 - Combustible liquids
• Klasa zagrożenia wodnego (WGK): WGK 2
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable