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Key Documents

AB5714

Sigma-Aldrich

Anti-Hey 1/HRT1 Antibody

Chemicon®, from rabbit

Synonim(y):

Anti-BHLHb31, Anti-HERP2, Anti-HESR1, Anti-HRT-1, Anti-NERP2, Anti-OAF1, Anti-hHRT1

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About This Item

Kod UNSPSC:
12352203
eCl@ss:
32160702
NACRES:
NA.41

pochodzenie biologiczne

rabbit

Poziom jakości

forma przeciwciała

saturated ammonium sulfate (SAS) precipitated

rodzaj przeciwciała

primary antibodies

klon

polyclonal

oczyszczone przez

affinity chromatography

reaktywność gatunkowa

human, mouse

producent / nazwa handlowa

Chemicon®

metody

immunohistochemistry: suitable
western blot: suitable

numer dostępu NCBI

numer dostępu UniProt

Warunki transportu

dry ice

docelowa modyfikacja potranslacyjna

unmodified

informacje o genach

human ... HEY1(23462)

Specyficzność

Recognizes Hey 1 / HRT1, a Helix-loop-helix class of transcription factor.

Immunogen

Synthetic peptide, amino acids 207-220 of human Hey 1 / HRT1.

Zastosowanie

Anti-Hey 1/HRT1 Antibody detects level of Hey 1/HRT1 & has been published & validated for use in WB, IH.
Research Category
Neuroscience
Research Sub Category
Developmental Neuroscience

Neuronal & Glial Markers
Western blot: 1:200-1:1,000 using ECL.

Immunohistochemistry: 1:200-1:1,000.

Optimal working dilutions must be determined by the end user.

Postać fizyczna

Precipitated antibody in a solution of 50% saturated ammonium sulfate and PBS containing no preservatives.

Przechowywanie i stabilność

Maintain unopened vial at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.

The rehydrated antibody solutions can be stored undiluted at 2-8°C for 2 months without any significant loss of activity. Note, the solution is not sterile, thus care should be taken if product is stored at 2-8°C.


For storage at -20°C, the addition of an equal volume of glycerol can be used, however, it is recommended that ACS grade or higher glycerol be used, as significant loss of activity can occur if the glycerol used is not of high quality.

For freezing, it is recommended that the rehydrated antibody solution be further diluted 1:1 with a 2% BSA (fraction V, highest-grade available) solution made with the rehydration buffer. The resulting 1% BSA/antibody solution can be aliquoted and stored frozen at -70°C for up to 6 months. Avoid repeated freeze/thaw cycles.

Informacje prawne

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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Kod klasy składowania

12 - Non Combustible Liquids

Klasa zagrożenia wodnego (WGK)

WGK 2

Temperatura zapłonu (°F)

Not applicable

Temperatura zapłonu (°C)

Not applicable


Certyfikaty analizy (CoA)

Poszukaj Certyfikaty analizy (CoA), wpisując numer partii/serii produktów. Numery serii i partii można znaleźć na etykiecie produktu po słowach „seria” lub „partia”.

Masz już ten produkt?

Dokumenty związane z niedawno zakupionymi produktami zostały zamieszczone w Bibliotece dokumentów.

Odwiedź Bibliotekę dokumentów

Esther C Broner et al.
Frontiers in oncology, 11, 677051-677051 (2021-08-03)
Despite recent advancements, the 5 year survival of head and neck squamous cell carcinoma (HNSCC) hovers at 60%. DCLK1 has been shown to regulate epithelial-to-mesenchymal transition as well as serving as a cancer stem cell marker in colon, pancreatic and
Syamantak Majumder et al.
Cell reports, 17(10), 2532-2541 (2016-12-08)
The spatiotemporal localization and expression of Dll4 are critical for sprouting angiogenesis. However, the related mechanisms are poorly understood. Here, we show that G-protein-coupled receptor-kinase interacting protein-1 (GIT1) is a robust endogenous inhibitor of Dll4-Notch1 signaling that specifically controls stalk cell
Qiushi Lin et al.
Molecular cancer, 18(1), 156-156 (2019-11-07)
Aspartate β-hydroxylase (ASPH) is silent in normal adult tissues only to re-emerge during oncogenesis where its function is required for generation and maintenance of malignant phenotypes. Exosomes enable prooncogenic secretome delivering and trafficking for long-distance cell-to-cell communication. This study aims
Activation of notch signaling in a xenograft model of brain metastasis.
Nam, DH; Jeon, HM; Kim, S; Kim, MH; Lee, YJ; Lee, MS; Kim, H; Joo, KM; Lee, DS; Price et al.
Clinical cancer research : an official journal of the American Association for Cancer Research null
Keith Hoek et al.
Cancer research, 64(15), 5270-5282 (2004-08-04)
Affymetrix and spotted oligonucleotide microarrays were used to assess global differential gene expression comparing normal human melanocytes with six independent melanoma cell strains from advanced lesions. The data, validated at the protein level for selected genes, confirmed the overexpression in

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