AB10514P

Anti-Serotonin Transporter Antibody

1 mg/mL, from rabbit

• Synonim(y): solute carrier family 6 (neurotransmitter transporter, serotonin), member 4, sodium-dependent serotonin transporter, serotonin transporter, Solute carrier family 6 member 4, Na+/Cl- dependent serotonin transporter, 5HT transporter, 5-hydroxytryptamine tr
• Kod UNSPSC: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Właściwości

• pochodzenie biologiczne: rabbit
• Poziom jakości: 100
• forma przeciwciała: affinity isolated antibody
• rodzaj przeciwciała: primary antibodies
• klon: polyclonal
• oczyszczone przez: affinity chromatography
• reaktywność gatunkowa (przewidywana na podstawie homologii): sheep (100% homology), rat (100% homology), bovine (100% homology), monkey (100% homology), human (100% homology), horse (100% homology), mouse (100% homology), chimpanzee (100% homology)
• stężenie: 1 mg/mL
• metody: western blot: suitable
• numer dostępu UniProt: P31645
• Warunki transportu: wet ice
• docelowa modyfikacja potranslacyjna: unmodified
• informacje o genach: human ... HTT(3064)

Opis

Opis ogólny

This gene encodes an integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. The encoded protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is a target of psychomotor stimulants, such as amphetamines and cocaine, and is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.

Specyficzność

Other species have not been tested.

The antibody reacts with the 70 kDa serotonin transporter protein.

Immunogen

Epitope: Center region

This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human serotonin transporter.

Zastosowanie

Research Category
Neuroscience

Research Sub Category
Ion Channels & Transporters

This Anti-Serotonin Transporter Antibody is validated for use in WB for the detection of Serotonin Transporter.

Jakość

Western Blot Analysis: 1:1000 dilution of this antibody detected serotonin transporter on human lung lysate.

Opis wartości docelowych

70 kDa

Powiązanie

Replaces: AB1594P

Postać fizyczna

Antigen Affinity Purified

Purified in 0.1M Tris-Glycine (pH7.4) 150mM NaCl with 0.05% NaN3.

Przechowywanie i stabilność

Store at 2-8°C for 1 year from date of receipt.

Komentarz do analizy

Control
Western Blot : Human lung lysate.

Oświadczenie o zrzeczeniu się odpowiedzialności

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable