487920

S-Nitrosoglutathione

≥95% (HPLC), solid, nitric oxide carrier, Calbiochem^®

• Synonim(y): S-Nitrosoglutathione, GSNO, SNOG
• Wzór empiryczny (zapis Hilla): C₁₀H₁₆N₄O₇S
• Numer CAS: 57564-91-7
• Masa cząsteczkowa: 336.32
• Numer MDL: MFCD00214341
• Kod UNSPSC: 12352200
• NACRES: NA.77

Właściwości

• product name: S-Nitrosoglutathione, A utility carrier of nitric oxide.
• Poziom jakości: 100
• Próba: ≥95% (HPLC)
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; desiccated (hygroscopic); protect from light
• kolor: pink
• rozpuszczalność: water: 10 mg/mL
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• InChI: 1S/C10H16N4O7S/c11-5(10(19)20)1-2-7(15)13-6(4-22-14-21)9(18)12-3-8(16)17/h5-6H,1-4,11H2,(H,12,18)(H,13,15)(H,16,17)(H,19,20)/t5-,6-/m0/s1
• Klucz InChI: HYHSBSXUHZOYLX-WDSKDSINSA-N

Opis

Opis ogólny

A utility carrier of nitric oxide. Breaks down at physiological pH to produce nitric oxide. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

A utility carrier of nitric oxide. Breaks down to produce nitric oxide and a glutathione radical at pH 7.4. Causes smooth muscle relaxation and inhibits platelet aggregation. Induces apoptosis in mouse thymocytes. Note: 1 set = 5 x 2.5 mg.

Działania biochem./fizjol.

Cell permeable: no

Primary Target
A utility carrier of nitric oxide

Product does not compete with ATP.

Reversible: no

Opakowanie

Packaged under inert gas

Ostrzeżenie

Toxicity: Standard Handling (A)

Rekonstytucja

Following reconstitution, aliquot and freeze (-20°C). Stock solutions are stable for up to 1 month at -20°C or for up to 2 h at 4°C.

Reconstitute in cold distilled H₂O (4°C) free of divalent cations other than Ca²⁺.

Inne uwagi

Sandau, K., et al. 1996. Cell Signal.8, 173.
Askew, S.C. 1995. Bioorg. Med. Chem.3, 1.
Fehsel, K., et al. 1995. J. Immunol.155, 2858.
de Belder, A.J., et al. 1994. Cardiovasc. Res.28, 691.
Sexton, D.J., et al. 1994. Photochem. Photobiol.59, 463.
Singh, R.J., et al. 1994. FEBS Lett. 360, 47.
Merryman, P.F., et al. 1993. Arthritis Rheum.36, 1414.
Park, J.W., et al. 1993. Biochem. Mol. Biol. Int.30, 885.
Radomski, M.W., et al. 1992. Br. J. Pharmacol.107, 745.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3