345802

Gc-Globulin, Mixed Type, Human Plasma

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

• Synonim(y): Gc-Globulin, Mixed Type, Human Plasma
• Numer CAS: 68476-36-8
• Kod UNSPSC: 12352202
• NACRES: NA.25

Właściwości

• pochodzenie biologiczne: human plasma
• Poziom jakości: 100
• Próba: ≥95% (SDS-PAGE)
• Postać: solid
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Opis ogólny

Native Gc-globulin from human plasma. A single polypeptide chain present in plasma at a concentration of about 20-55 mg/100 ml. Functions in the binding and transport of vitamin D. May also play an important role in actin homeostasis; binds monomeric actin with high affinity. Binds membranes of both circulating B and T lymphocytes.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D.

Native Gc-globulin from human plasma. Single polypeptide chain present in plasma at about 20-55 mg/dl. Functions in binding and transport of vitamin D. May also play an important role in actin homeostasis as it has been shown to bind monomeric actin with high affinity. Binds to cell surface at the DBP binding site in a nonsaturable manner.

Zastosowanie

Gc-Globulin, Mixed Type, Human Plasma, CAS 68476-36-8, is a single polypeptide chain that transports vitamin D. Binds to cell surface at the DBP binding site in a non-saturable manner.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

Lyophilized from 150 mM NaCl, 20 mM sodium phosphate buffer, pH 7.4.

Uwaga dotycząca przygotowania

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Rekonstytucja

Following reconstitution, aliquot and freeze (-70°C). Stock solutions are stable for up to 1 year at -70°C.

Inne uwagi

Di Martino, S.J., and Kew, R.R. 1999. J. Immunol. 163, 2135.
Lee, W.M., et al. 1987. Hepatology7, 825.
Machii, T., et al. 1986. Acta Haematol.75, 26.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3