345749

GDF-8 Propeptide

≥90% (SDS-PAGE), lyophilized powder, mouse

• Kod UNSPSC: 12352203
• NACRES: NA.26

Właściwości

• Nazwa produktu: GDF-8 Propeptide, His•Tag^®, Mouse, Recombinant, GDF-8 Propeptide, His•Tag, Mouse, Recombinant, consists of amino acids 25-285, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells.
• rekombinowane: expressed in mouse NSO cells (myeloma cells)
• Poziom jakości: 100
• Próba: ≥90% (SDS-PAGE)
• Formularz: lyophilized
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze
• zanieczyszczenia: ≤1.0 EU/μg protein Endotoxin
• Warunki transportu: ambient
• temp. przechowywania: −20°C

Opis

Opis ogólny

Recombinant, mouse growth differentiation factor-8 (GDF-8)/myostatin propeptide, consisting of amino acids 25-285, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells. GDF-8 is a secreted protein that is expressed during embryonic development and in adult skeletal muscle.

Zastosowanie

GDF-8 Propeptide, His•Tag, Mouse, Recombinant, consists of amino acids 25-285, fused at the C-terminus to a His•Tag sequence, and expressed in NS0-derived mouse myeloma cells.

Działania biochem./fizjol.

ED₅₀ = 0.05-0.25 µg/ml (using 40 ng/ml rmGDF-8) as measured by inhibition of rmGDF-8 activity in K562 human chronic myelogenous leukemia cells. Approximately 1 µg/ml will completely inhibit GDF-8 activity in K562 cells.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

Lyophilized from 0.2 µm filtered PBS, BSA.

Rekonstytucja

Following reconstituyion refrigerate (4°C) for short-term storage or aliquot and freeze (-20°C) for long-term storage. Stock solutions are stable for up to 1 month at 4°C or for up to 3 months at -20°C.

Reconstitute to 50 µg/ml with sterile PBS containing ≥1% human or bovine serum albumin.

Inne uwagi

Hill, J.J. et al. 2003. Molecular Endocrinology17, 1144.
Thies, R.S. et al. 2001. Growth Factors18, 251.
Chang, H. et al. 2002. Endocrine Reviews23, 787.
McPherron, A.C. et al. 1997. Nature387, 83.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

HIS TAG is a registered trademark of Merck KGaA, Darmstadt, Germany

Ta strona może zawierać tekst przetłumaczony maszynowo.

Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 2