204870-M

Complement C3d, Human

Complement C3d, Human is a native, 30 kDa polypeptide formed by the limited digestion of iC3b by trypsin or elastin. The binding of C3d to CR2 on B lymphocytes enhances B cell activation.

• Kod UNSPSC: 12352202

Właściwości

• Poziom jakości: 100
• Próba: ≥85% (SDS-PAGE)
• Postać: liquid
• nie zawiera: preservative
• producent / nazwa handlowa: Calbiochem^®
• warunki przechowywania: OK to freeze; avoid repeated freeze/thaw cycles
• zanieczyszczenia: IgG, IgM, IgA, C5, Factor H, Factor I, trace
• temp. przechowywania: −70°C

Opis

Opis ogólny

Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30 kDa. The binding of C3d to CR2 (CD21) receptors present on B lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.

Native, human C3d complement component. C3d is formed by the limited digestion of iC3b by trypsin or elastin. The C3d region of C3 contains the portion of the native C3 molecule which is capable of forming a covalent bond attachment to target surfaces under attack by complement. C3d is a polypeptide of M.W. 30,000. The binding of C3d to CR2 (CD21) receptors present on B-lymphocytes markedly enhances B cell activation initiated by a wide variety of stimuli.

Ostrzeżenie

Toxicity: Standard Handling (A)

Postać fizyczna

In PBS, pH 7.2.

Uwaga dotycząca przygotowania

Prepared from serum that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Rekonstytucja

Following initial thaw, aliquot and freeze (-20°C).

Inne uwagi

Luxembourg, A.T. and Cooper, N.R. 1994. J. Immunol.153, 4448.
Lambris, J.D., et al. 1985. Proc. Natl. Acad. Sci. USA82, 4235.

Informacje prawne

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 12 - Non Combustible Liquids
• Klasa zagrożenia wodnego (WGK): nwg
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable