H-101

trans-3′-Hydroxycotinine solution

1.0 mg/mL in methanol, ampule of 1 mL, certified reference material, Cerilliant^®

• Wzór empiryczny (zapis Hilla): C₁₀H₁₂N₂O₂
• Numer CAS: 34834-67-8
• Masa cząsteczkowa: 192.21
• Kod UNSPSC: 41116107
• NACRES: NA.24

Właściwości

• klasa czystości: certified reference material
• Postać: liquid
• Właściwości: (Snap-N-Spike^®)
• opakowanie: ampule of 1 mL
• producent / nazwa handlowa: Cerilliant^®
• stężenie: 1.0 mg/mL in methanol
• metody: gas chromatography (GC): suitable; liquid chromatography (LC): suitable
• Zastosowanie: forensics and toxicology
• format: single component solution
• temp. przechowywania: −20°C
• ciąg SMILES: CN1[C@H](C2=CN=CC=C2)C[C@@H](O)C1=O
• InChI: 1S/C10H12N2O2/c1-12-8(5-9(13)10(12)14)7-3-2-4-11-6-7/h2-4,6,8-9,13H,5H2,1H3/t8-,9+/m0/s1
• Klucz InChI: XOKCJXZZNAUIQN-DTWKUNHWSA-N

Opis

Opis ogólny

Trans-3′-Hydroxycotinine is a major nicotine metabolite excreted in the urine of smokers and users of other tobacco or nicotine products including cigars, chewing tobacco and snuff. This Certified Spiking Solution^® is suitable for use in nicotine testing methods or clinical and diagnostic testing of nicotine biomarkers by LC-MS/MS or GC/MS.

Zastosowanie

• Wastewater-Based Tobacco Use Estimates: trans-3′-Hydroxycotinine is used as WBE biomarkers to to estimate tobacco use. It has significantly improved wastewater-based tobacco use estimates. This application enhances our understanding of public health trends by providing more accurate measurements of tobacco consumption in populations, using advanced environmental monitoring techniques (Zheng et al., 2023).


• Predicting Nicotine Metabolism: Trans-3′-Hydroxycotinine is utilized in genomic studies to predict nicotine metabolism across different ancestries, which helps in tailoring smoking cessation therapies based on individual genetic profiles.(Baurley et al., 2022).

Informacje prawne

CERILLIANT is a registered trademark of Merck KGaA, Darmstadt, Germany

CERTIFIED SPIKING SOLUTION is a registered trademark of Cerilliant Corporation

Snap-N-Spike is a registered trademark of Merck KGaA, Darmstadt, Germany

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Informacja o środkach bezpieczeństwa

• Piktogramy: GHS02,GHS06,GHS08
• Hasło ostrzegawcze: Danger
• Zwroty wskazujące rodzaj zagrożenia: H225,H301 + H311 + H331,H370
• Zwroty wskazujące środki ostrożności: P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311
• Klasyfikacja zagrożeń: Acute Tox. 3 Dermal - Acute Tox. 3 Inhalation - Acute Tox. 3 Oral - Flam. Liq. 2 - STOT SE 1
• Organy docelowe: Eyes
• Kod klasy składowania: 3 - Flammable liquids
• Klasa zagrożenia wodnego (WGK): WGK 1
• Temperatura zapłonu (°F): 49.5 °F
• Temperatura zapłonu (°C): 9.7 °C