780200P
Avanti
16:0 PE MCC
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt), powder
Synonim(y):
1,2-dihexadecanoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (sodium salt)
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About This Item
Wzór empiryczny (zapis Hilla):
C49H86N2O11PNa
Numer CAS:
Masa cząsteczkowa:
933.18
Kod UNSPSC:
12352211
NACRES:
NA.25
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Próba
>99% (TLC)
Postać
powder
opakowanie
pkg of 1 × 25 mg (780200P-25mg)
producent / nazwa handlowa
Avanti Research™ - A Croda Brand 780200P
Warunki transportu
dry ice
temp. przechowywania
−20°C
Opis ogólny
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide] (16:0 PE MCC) is a lipid consisting of phosphoethanolamine linked to two palmitic acid through its phosphate group and to a maleimide group by its amino group. It is a maleimide-functionalized lipid.
Zastosowanie
16:0 PE MCC (1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide]) may been used in functionalized liposome preparation for drug delivery. It may also be used in liposome preparation for testing drug delivery functionality and as a component in microbubble dispersions.
Działania biochem./fizjol.
1,2-dipalmitoyl-sn-glycero-3-phosphoethanolamine-N-[4-(p-maleimidomethyl)cyclohexane-carboxamide](DPPE-MCC) via the maleimide group enables covalent attachment in functionalized liposomes and is useful in peptide transport studies.
Opakowanie
5 mL Amber Glass Screw Cap Vial (780200P-25mg)
Informacje prawne
Avanti Research is a trademark of Avanti Polar Lipids, LLC
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Kod klasy składowania
11 - Combustible Solids
Certyfikaty analizy (CoA)
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Journal of controlled release : official journal of the Controlled Release Society, 172(3), 872-878 (2013-10-22)
The aim of the present study was the in vivo evaluation of thiomer-coated liposomes for an oral application of peptides. For this purpose, salmon calcitonin was chosen as a model drug and encapsulated within liposomes. Subsequently, the drug loaded liposomes
K Gradauer et al.
Journal of controlled release : official journal of the Controlled Release Society, 165(3), 207-215 (2012-12-12)
An ideal oral drug carrier should facilitate drug delivery to the gastrointestinal tract and its absorption into the systemic circulation. To meet these requirements, we developed a thiomer-coated liposomal delivery system composed of 1,2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) and a maleimide-functionalized lipid, to
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