QBD10260

m-dPEG^®₈-NHS ester

• Synonim(y): 2,5,8,11,14,17,20,23-Octaoxahexacosan-26-oic acid succinimidyl ester, 2,5-Dioxo-1-pyrrolidinyl 4,7,10,13,16,19,22,25-octaoxahexacosanoate, Polyethylene glycol
• Wzór empiryczny (zapis Hilla): C₂₂H₃₉NO₁₂
• Numer CAS: 756525-90-3
• Masa cząsteczkowa: 509.54
• Numer MDL: MFCD13184969
• Kod UNSPSC: 12352108
• Identyfikator substancji w PubChem: 329823901
• NACRES: NA.22

Właściwości

• Próba: >90%
• Postać: solid or viscous liquid
• przydatność reakcji: reagent type: chemical modification reagent; reagent type: cross-linking reagent; reactivity: amine reactive
• architektura polimerowa: shape: linear; functionality: monofunctional
• Warunki transportu: ambient
• temp. przechowywania: −20°C
• ciąg SMILES: O=C(CCOCCOCCOCCOCCOCCOCCOCCOC)ON1C(CCC1=O)=O
• InChI: 1S/C22H39NO12/c1-27-6-7-29-10-11-31-14-15-33-18-19-34-17-16-32-13-12-30-9-8-28-5-4-22(26)35-23-20(24)2-3-21(23)25/h2-19H2,1H3
• Klucz InChI: IBZNTYBFTKFSMU-UHFFFAOYSA-N

Opis

Cechy i korzyści

The m-dPEG^®₈-NHS ester provides a variety of means to modify small molecules, peptides, proteins, and functionalized surfaces (metals, glass, and others). The single molecular weight methoxy-terminated dPEG^® molecules are hydrophilic and non-immunogenic of exact length. Modification with m-dPEG^® reagents can improve water solubility, increase hydrodynamic volume, eliminate or reduce non-specific binding, protect peptides and proteins from proteolysis, reduce or eliminate immunogenicity, and increase serum half-life in vivo. The m-dPEG^®₈-NHS ester reacts with amines.

Informacje prawne

Products Protected under U.S. Patents # 7,888,536 B2

dPEG is a registered trademark of Quanta BioDesign

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Informacja o środkach bezpieczeństwa

• Kod klasy składowania: 11 - Combustible Solids
• Klasa zagrożenia wodnego (WGK): WGK 3
• Temperatura zapłonu (°F): Not applicable
• Temperatura zapłonu (°C): Not applicable