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UCP2

uncoupling protein 2 (mitochondrial, proton carrier)

Synonimy:
BMIQ4, SLC25A8, UCPH
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(7351) Summary: Mitochondrial uncoupling proteins (UCP) are members of the larger family of mitochondrial anion carrier proteins (MACP). UCPs separate oxidative phosphorylation from ATP synthesis with energy dissipated as heat, also referred to as the mitochondrial proton leak. UCPs facilitate the transfer of anions from the inner to the outer mitochondrial membrane and the return transfer of protons from the outer to the inner mitochondrial membrane. They also reduce the mitochondrial membrane potential in mammalian cells. Tissue specificity occurs for the different UCPs and the exact methods of how UCPs transfer H+/OH- are not known. UCPs contain the three homologous protein domains of MACPs. This gene is expressed in many tissues, with the greatest expression in skeletal muscle. It is thought to play a role in nonshivering thermogenesis, obesity and diabetes. Chromosomal order is 5'-UCP3-UCP2-3'. [provided by RefSeq, Jul 2008]
  • Mouse(22228) uncoupling protein 2 (mitochondrial, proton carrier)
  • Rat(54315) uncoupling protein 2 (mitochondrial, proton carrier)
  • naked mole-rat(101713667) uncoupling protein 2 (mitochondrial, proton carrier)
  • domestic guinea pig(100727277) uncoupling protein 2 (mitochondrial, proton carrier)
  • cow(281562) uncoupling protein 2 (mitochondrial, proton carrier)
  • sheep(641300) uncoupling protein 2 (mitochondrial, proton carrier)
  • sheep(101104932) uncoupling protein 2 (mitochondrial, proton carrier)
  • Thale Cress(836014) uncoupling protein 2
  • domestic cat(692194) uncoupling protein 2 (mitochondrial, proton carrier)
  • dog(403576) uncoupling protein 2 (mitochondrial, proton carrier)
  • Zebrafish(555812) uncoupling protein 2

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-Uncoupling Protein 2/UCP2 antibody produced in goat, affinity isolated antibody, buffered aqueous solution,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
ELISA
immunofluorescence

western blot
Anti-Uncoupling Protein 2 Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
human
Zastosowanie
ELISA
western blot
Anti-Uncoupling Protein 2 Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
western blot
Anti-Uncoupling Protein-2 (UCP-2) (144-157) Rabbit pAb, liquid, Calbiochem®,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
Anti-Uncoupling Protein 2 Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
mouse
Zastosowanie
ELISA
western blot

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human UCP2,
Gatunek
human
MISSION® esiRNA, targeting mouse Ucp2,
Gatunek
mouse