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Merck

RBPJ

recombination signal binding protein for immunoglobulin kappa J region

Synonimy:
AOS3, CBF1, IGKJRB, IGKJRB1, KBF2, RBP-J, RBPJK, RBPSUH, SUH, csl
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3516) Summary: The protein encoded by this gene is a transcriptional regulator important in the Notch signaling pathway. The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins. It is thought to function by recruiting chromatin remodeling complexes containing histone deacetylase or histone acetylase proteins to Notch signaling pathway genes. Also, this protein can bind specifically to the recombination signal sequence of immunglobulin kappa type J segments. Several transcript variants encoding different isoforms have been found for this gene, and several pseudogenes of this gene exist on chromosome 9. [provided by RefSeq, Oct 2011]
  • Mouse(19664) recombination signal binding protein for immunoglobulin kappa J region
  • Rat(679028) recombination signal binding protein for immunoglobulin kappa J region
  • chicken(422802) recombination signal binding protein for immunoglobulin kappa J region
  • Horse(100055547) recombination signal binding protein for immunoglobulin kappa J region
  • domestic cat(101100207) recombination signal binding protein for immunoglobulin kappa J region
  • dog(479122) recombination signal binding protein for immunoglobulin kappa J region
  • domestic guinea pig(100716535) recombination signal binding protein for immunoglobulin kappa J region
  • naked mole-rat(101726624) recombination signal binding protein for immunoglobulin kappa J region
  • cow(767928) recombination signal binding protein for immunoglobulin kappa J region
  • sheep(101107196) recombination signal binding protein for immunoglobulin kappa J region

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-RBPJK antibody produced in rabbit, ,
Reaktywność gatunkowa
mouse, rat
Zastosowanie
immunohistochemistry
western blot
Anti-RBP-Jk Antibody, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ChIP
immunohistochemistry

western blot
Anti-RBPJ Antibody, serum, from rabbit,
Reaktywność gatunkowa
human, mouse, primate
Zastosowanie
ChIP
western blot
Anti-RBPJ antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, rabbit, rat
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-RBP-Jk, clone 1F1 Antibody, clone 1F1, from rat,
Reaktywność gatunkowa
drosophila, human
Zastosowanie
ChIP
electrophoretic mobility shift assay

immunoprecipitation (IP)

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human RBPJ,
Gatunek
human
MISSION® esiRNA, targeting mouse Rbpj,
Gatunek
mouse