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PADI2

peptidyl arginine deiminase, type II

Synonimy:
PAD-H19, PAD2, PDI2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(11240) Summary: This gene encodes a member of the peptidyl arginine deiminase family of enzymes, which catalyze the post-translational deimination of proteins by converting arginine residues into citrullines in the presence of calcium ions. The family members have distinct substrate specificities and tissue-specific expression patterns. The type II enzyme is the most widely expressed family member. Known substrates for this enzyme include myelin basic protein in the central nervous system and vimentin in skeletal muscle and macrophages. This enzyme is thought to play a role in the onset and progression of neurodegenerative human disorders, including Alzheimer disease and multiple sclerosis, and it has also been implicated in glaucoma pathogenesis. This gene exists in a cluster with four other paralogous genes. [provided by RefSeq, Jul 2008]
  • Mouse(18600) peptidyl arginine deiminase, type II
  • Rat(29511) peptidyl arginine deiminase, type II
  • Zebrafish(386792) peptidyl arginine deiminase, type II
  • cow(617851) peptidyl arginine deiminase, type II
  • Horse(100050025) peptidyl arginine deiminase, type II
  • domestic cat(101085301) peptidyl arginine deiminase, type II
  • chicken(428172) peptidyl arginine deiminase, type II
  • dog(487414) peptidyl arginine deiminase, type II
  • naked mole-rat(101721485) peptidyl arginine deiminase, type II
  • domestic guinea pig(100728531) peptidyl arginine deiminase, type II
  • sheep(101108464) peptidyl arginine deiminase, type II

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-PADI2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
bovine, dog, horse, human
Zastosowanie
western blot
Anti-PADI2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-PADI2/PAD2 Antibody, clone DN2, ,
Reaktywność gatunkowa
human, rabbit
Zastosowanie
ELISA
immunohistochemistry

multiplexing

western blot

Proteins

Numer produktu
Opis
Gatunek
PADI-2 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥60% (SDS-PAGE),
Gatunek
human
PAD2, GST tagged from mouse, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
mouse
PAD Cocktail, Active, recombinant,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting mouse Padi2,
Gatunek
mouse
MISSION® esiRNA, targeting human PADI2,
Gatunek
human