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MTOR

mechanistic target of rapamycin (serine/threonine kinase)

Synonimy:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-phospho-mTOR (pSer2448) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry

western blot
Monoklonalny anty-mTOR, clone GT6611, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
western blot
Monoklonalny anty-mTOR, clone GT649, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
immunohistochemistry
western blot
Monoclonal Anti-MTOR antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL8228, purified immunoglobulin, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Przeciwciało anty-mTOR, klon F11, clone F11, from mouse,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunoprecipitation (IP)
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Perhexiline maleate salt, ≥98% (HPLC),
Gatunek
human
PF-04691502, ≥98% (HPLC),
Gatunek
human

Proteins

Numer produktu
Opis
Gatunek
Białko mTOR (1362-end), aktywne, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Gatunek
human
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MTOR,
Gatunek
human