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Merck

MTOR

mechanistic target of rapamycin (serine/threonine kinase)

Synonimy:
FRAP, FRAP1, FRAP2, RAFT1, RAPT1
Gatunek:
Human MTOR (2475), Mouse Mtor (56717), Rat Mtor (56718), Zebrafish mtor (324254), cow MTOR (100139219), Horse MTOR (100051341), domestic cat MTOR (101098152), dog MTOR (478232), fruit fly Mtor (36264), chicken MTOR (419455) ...Więcej
Identyfikator UniProtKB:
P42345, Q4LE76, Q5TER1, Q6LE87, Q96QG3, Q9Y4I3
Identyfikator genu:
  • Human(2475) Summary: The protein encoded by this gene belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. The ANGPTL7 gene is located in an intron of this gene. [provided by RefSeq, Sep 2008]
  • Mouse(56717) mechanistic target of rapamycin (serine/threonine kinase)
  • Rat(56718) mechanistic target of rapamycin (serine/threonine kinase)
  • Zebrafish(324254) mechanistic target of rapamycin (serine/threonine kinase)
  • cow(100139219) mechanistic target of rapamycin (serine/threonine kinase)
  • Horse(100051341) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic cat(101098152) mechanistic target of rapamycin (serine/threonine kinase)
  • dog(478232) mechanistic target of rapamycin (serine/threonine kinase)
  • fruit fly(36264) Megator
  • chicken(419455) mechanistic target of rapamycin (serine/threonine kinase)
  • Domestic Rabbit(100356164) mechanistic target of rapamycin (serine/threonine kinase)
  • naked mole-rat(101725626) mechanistic target of rapamycin (serine/threonine kinase)
  • domestic guinea pig(100724938) mechanistic target of rapamycin (serine/threonine kinase)
  • Goat(100860902) mechanistic target of rapamycin (serine/threonine kinase)
  • sheep(100271659) mechanistic target of rapamycin (serine/threonine kinase)

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Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
HPA071227
Anty-MTOR, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
SAB5701822
Anti-Phospho-mTOR-S2481, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
SAB5700779
Przeciwciało anty-MTORprodukowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunoprecipitation (IP)
western blot
SAB5700687
Przeciwciało anty-MTORprodukowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
SAB4301526
Anty-fosfo-mTOR(pSer2481), affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot

Small Molecule - Inhibitor

Product Number
Opis
Gatunek
SML0120
Perhexiline maleate salt, ≥98% (HPLC),
Gatunek
human

Proteins

Product Number
Opis
Gatunek
14-770-M
Białko mTOR (1362-end), aktywne, 10 µg, Active, N-terminal FLAG-tagged, recombinant, human mTOR, amino acids 1362-end, for use in Kinase Assays.,
Gatunek
human
SRP0364
mTOR/Raptor/MLST8 human, recombinant, expressed in baculovirus infected Sf9 cells, ≥50% (SDS-PAGE),
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
EHU101641
MISSION® esiRNA, targeting human MTOR,
Gatunek
human