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Merck

MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Synonimy:
CLG4, CLG4A, MMP-II, MONA, TBE-1
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(4313) Summary: Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(17390) matrix metallopeptidase 2
  • Rat(81686) matrix metallopeptidase 2
  • domestic guinea pig(100719361) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Domestic Rabbit(100009000) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • naked mole-rat(101696977) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • sheep(443115) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Zebrafish(337179) matrix metalloproteinase 2
  • chicken(386583) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • fruit fly(35997) Matrix metalloproteinase 2
  • cow(282872) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • Horse(100033948) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • domestic cat(101098838) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)
  • dog(403733) matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

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ELISA

Numer produktu
Opis
Gatunek
Human MMP-2 ELISA Kit, for serum, plasma, cell culture supernatant,
Gatunek
human
Mouse MMP-2 ELISA Kit, for serum, plasma and cell culture supernatant,
Gatunek
mouse
Rat MMP-2 ELISA, for serum, plasma and cell culture supernatants,
Gatunek
rat

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-MMP-2 Antibody, catalytic domain, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunoprecipitation (IP)
western blot
Anty-MMP-2 (Ab-3) mysie mAb (42-5D11), liquid, clone 42-5D11, Calbiochem®,
Reaktywność gatunkowa
bovine, human, mouse, rat
Zastosowanie
Anti-MMP2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
Anty MMP2, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
Przeciwciało anty-MMP2produkowane u królików, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
PD166793 hydrate, ≥98% (HPLC),
Gatunek
human, rat, mouse
Marimastat, ≥98% (HPLC),
Gatunek
human, rat, mouse
CP-471474, ≥98% (HPLC),
Gatunek
human, rat, mouse
CP-101537, ≥98% (HPLC),
Gatunek
human, rat, mouse

Proteins

Numer produktu
Opis
Gatunek
MMP-2 human, recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), suitable for cell culture,
Gatunek
human
Matrix Metalloproteinase-2 human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Gatunek
human
Matrix Metalloproteinase-2 from mouse, recombinant, expressed in NSO cells, >95% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
mouse, rat

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human MMP2,
Gatunek
human
MISSION® esiRNA, targeting mouse Mmp2,
Gatunek
mouse