LATS2
large tumor suppressor kinase 2
Synonimy:
KPM
Gatunek:
Human LATS2 (26524), Mouse Lats2 (50523), Rat Lats2 (305922), Zebrafish lats2 (567674), cow LATS2 (508208), Horse LATS2 (100050150), domestic cat LATS2 (101093824), dog LATS2 (477343), chicken LATS2 (418949), domestic guinea pig Lats2 (100725954) ...Więcej
Identyfikator UniProtKB:
Identyfikator genu:
- Human(26524) Summary: This gene encodes a serine/threonine protein kinase belonging to the LATS tumor suppressor family. The protein localizes to centrosomes during interphase, and early and late metaphase. It interacts with the centrosomal proteins aurora-A and ajuba and is required for accumulation of gamma-tubulin and spindle formation at the onset of mitosis. It also interacts with a negative regulator of p53 and may function in a positive feedback loop with p53 that responds to cytoskeleton damage. Additionally, it can function as a co-repressor of androgen-responsive gene expression. [provided by RefSeq, Jul 2008]
- Mouse(50523) large tumor suppressor 2
- Rat(305922) large tumor suppressor 2
- Zebrafish(567674) LATS, large tumor suppressor, homolog 2 (Drosophila)
- cow(508208) large tumor suppressor kinase 2
- Horse(100050150) LATS, large tumor suppressor, homolog 2 (Drosophila)
- domestic cat(101093824) LATS, large tumor suppressor, homolog 2 (Drosophila)
- dog(477343) LATS, large tumor suppressor, homolog 2 (Drosophila)
- chicken(418949) LATS, large tumor suppressor, homolog 2 (Drosophila)
- domestic guinea pig(100725954) large tumor suppressor kinase 2
- naked mole-rat(101705060) large tumor suppressor kinase 2
- sheep(101117941) LATS, large tumor suppressor, homolog 2 (Drosophila)
- Domestic Rabbit(100356876) LATS, large tumor suppressor, homolog 2 (Drosophila)
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-LATS2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunofluorescence
immunohistochemistry
immunofluorescence
immunohistochemistry
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-LATS2 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
Anti-phospho-LATS1/2 (pThr1079/1041) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
immunohistochemistry
Anti-phospho-LATS1-T1079/LATS2-T1041 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
western blot
Proteins
Numer produktu
Opis
Gatunek
LATS2 (480-1088), GST tagged human, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Gatunek
human
esiRNA
Numer produktu
Opis
Gatunek