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KDR

kinase insert domain receptor (a type III receptor tyrosine kinase)

Synonimy:
CD309, FLK1, VEGFR, VEGFR2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(3791) Summary: Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
  • Mouse(16542) kinase insert domain protein receptor
  • Rat(25589) kinase insert domain receptor
  • Goat(100860836) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • sheep(443087) vascular endothelial growth factor receptor-2
  • Domestic Rabbit(100008607) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic guinea pig(100726761) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • naked mole-rat(101726029) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Zebrafish(554230) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • cow(407170) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Horse(100033959) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • domestic cat(101090260) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • dog(482154) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • chicken(395323) kinase insert domain receptor (a type III receptor tyrosine kinase)
  • Thale Cress(839585) basic helix-loop-helix protein KIDARI

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ELISA

Numer produktu
Opis
Gatunek
Human VEGF R2 ELISA Kit, for serum, plasma, cell culture supernatant and urine,
Gatunek
human
Mouse Kdr / Vascular Endothelial Growth Factor Receptor 2 ELISA Kit, ,
Gatunek
mouse

Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Przeciwciało anty-KDR/Flk-1/VEGFR2, klon CH-11, clone CH-11, Upstate®, from mouse,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunocytochemistry

western blot
Przeciwciało anty-fosfoVEGFR2/Flk-1/KDR (Tyr1054), Upstate®, from rabbit,
Reaktywność gatunkowa
danio, bovine, chicken, horse, human, mouse, primate, rat, zebrafish
Zastosowanie
western blot
Przeciwciało anty-fosfo-KDR/Flk-1/VEGFR2 (Tyr1054), klon D1W, królicze monoklonalne, culture supernatant, clone D1W, Upstate®,
Reaktywność gatunkowa
human, mouse
Zastosowanie
western blot
Anti-Vascular Endothelial Growth Factor Receptor-2 (KDR)−Biotin Conjugate antibody, Mouse monoclonal, clone 260.4, KDR-2, purified from hybridoma cell culture,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-VEGFR2 antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse
Zastosowanie
ELISA
immunohistochemistry

western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
7-Cyclopentyl-5-(4-phenoxyphenyl)-7H-pyrrolo[2,3‑d]pyrimidin-4-ylamine, ≥98% (HPLC),
Gatunek
human
SU 5416, ≥98% (HPLC),
Gatunek
human, mouse
Pazopanib, ,
Gatunek
human
α-Sexithiophene, ,
Gatunek
human, rat

Proteins

Numer produktu
Opis
Gatunek
Białko KDR, aktywne, 10 µg, Active, N-terminal His6-tagged, recombinant, human KDR amino acids 790-end,
for use in Kinase Assays.
,
Gatunek
human
VEGF Receptor-2 (Flk-1, KDR)/Fc Chimera human, >90% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder,
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human KDR,
Gatunek
human
MISSION® esiRNA, targeting mouse Kdr,
Gatunek
mouse