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HCN4

hyperpolarization activated cyclic nucleotide-gated potassium channel 4

Synonimy:
SSS2
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(10021) Summary: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]
  • Mouse(330953) hyperpolarization-activated, cyclic nucleotide-gated K+ 4
  • Rat(59266) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic guinea pig(100717049) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • naked mole-rat(101715130) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • sheep(101117337) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Domestic Rabbit(100009452) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • Zebrafish(557843) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • cow(785689) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • domestic cat(101090363) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • dog(448794) hyperpolarization activated cyclic nucleotide-gated potassium channel 4
  • chicken(427478) hyperpolarization activated cyclic nucleotide-gated potassium channel 4

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anty-HCN4, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human
Zastosowanie
immunofluorescence
immunohistochemistry
Monoclonal Anti-HCN4 antibody produced in mouse, clone S114-10, 1 mg/mL, purified immunoglobulin,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunocytochemistry
immunohistochemistry

western blot
Anty-HCN4, affinity isolated antibody,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
Anti-HCN4 Antibody, clone PG2-1A4, clone PG2-1A4, from rat,
Reaktywność gatunkowa
mouse
Zastosowanie
electron microscopy
immunofluorescence

immunohistochemistry

western blot
Przeciwciało anty-HCN4, Chemicon®, from rabbit,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot

Small Molecule - Blocker

Numer produktu
Opis
Gatunek
Ivabradine hydrochloride, ≥98% (HPLC),
Gatunek
human
Dronedarone hydrochloride, ≥98% (HPLC),
Gatunek
human
Dronedarone hydrochloride, United States Pharmacopeia (USP) Reference Standard,
Gatunek
human
Dronedarone hydrochloride, European Pharmacopoeia (EP) Reference Standard,
Gatunek
human