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ATIC

5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

Synonimy:
AICAR, AICARFT, IMPCHASE, PURH
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(471) Summary: This gene encodes a bifunctional protein that catalyzes the last two steps of the de novo purine biosynthetic pathway. The N-terminal domain has phosphoribosylaminoimidazolecarboxamide formyltransferase activity, and the C-terminal domain has IMP cyclohydrolase activity. A mutation in this gene results in AICA-ribosiduria. [provided by RefSeq, Sep 2009]
  • Mouse(108147) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • Rat(81643) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • Zebrafish(140622) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • dog(488513) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • Horse(100054298) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • cow(506343) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • domestic cat(101081485) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • chicken(396091) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • naked mole-rat(101721008) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • domestic guinea pig(100726313) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • sheep(101105137) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
  • Domestic Rabbit(100346623) 5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ATIC (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
guinea pig, human, mouse, rabbit, rat, yeast
Zastosowanie
western blot
Anti-ATIC antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot
Anti-ATIC antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry

western blot
Anti-ATIC antibody produced in rabbit, purified immunoglobulin, buffered aqueous solution,
Reaktywność gatunkowa
human
Zastosowanie
western blot

Small Molecule - Inhibitor

Numer produktu
Opis
Gatunek
Deoxycholic acid, ≥98% (HPLC),
Gatunek
human
Deoxycholic acid, ≥99.0% (T),
Gatunek
human
Ouabain octahydrate, ≥95% (HPLC), powder,
Gatunek
rat, human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ATIC,
Gatunek
human
MISSION® esiRNA, targeting mouse Atic,
Gatunek
mouse