ACTN4
actinin, alpha 4
Synonimy:
ACTININ-4, FSGS, FSGS1
Gatunek:
Human ACTN4 (81), Mouse Actn4 (60595), Rat Actn4 (63836), Zebrafish actn4 (322221), cow ACTN4 (522269), domestic cat ACTN4 (101093978), dog ACTN4 (484526), chicken ACTN4 (396024), sheep ACTN4 (101111737), domestic guinea pig Actn4 (100733111)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(81) Summary: Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a nonmuscle, alpha actinin isoform which is concentrated in the cytoplasm, and thought to be involved in metastatic processes. Mutations in this gene have been associated with focal and segmental glomerulosclerosis. [provided by RefSeq, Jul 2008]
- Mouse(60595) actinin alpha 4
- Rat(63836) actinin alpha 4
- Zebrafish(322221) actinin, alpha 4
- cow(522269) actinin, alpha 4
- domestic cat(101093978) actinin, alpha 4
- dog(484526) actinin, alpha 4
- chicken(396024) actinin, alpha 4
- sheep(101111737) actinin, alpha 4
- domestic guinea pig(100733111) actinin, alpha 4
- naked mole-rat(101710271) actinin, alpha 4
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ACTN4 (AB2) antibody produced in rabbit, IgG fraction of antiserum,
Reaktywność gatunkowa
bovine, dog, guinea pig, horse, human, mouse, rabbit, rat
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-Alpha Actinin-4 antibody, Rabbit Monoclonal, recombinant, expressed in HEK 293 cells, clone RM287, purified immunoglobulin,
Reaktywność gatunkowa
human
Zastosowanie
immunohistochemistry
western blot
western blot
Mysie mAb anty-ACTN4 (4D10), liquid, clone 4D10, Calbiochem®,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
Przeciwciało anty-α-aktynina 4, klon 1D9 10889 Królik monoklonalny, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human
Zastosowanie
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Przeciwciało anty-α-aktynina-4, klon 5Y3R6, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
immunoprecipitation (IP)
western blot
immunoprecipitation (IP)
western blot