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MilliporeSigma

ACLY

ATP citrate lyase

Synonimy:
ACL, ATPCL, CLATP
Gatunek:
Human ACLY (47), Mouse Acly (104112), Rat Acly (24159), chicken ACLY (395373), Horse ACLY (100053195), cow ACLY (511135), domestic cat ACLY (100422779), dog ACLY (607852), naked mole-rat Acly (101700349), domestic guinea pig Acly (100714933)
Identyfikator UniProtKB:
P53396, B4DIM0, Q13037, Q9BRL0
Identyfikator genu:
  • Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(104112) ATP citrate lyase
  • Rat(24159) ATP citrate lyase
  • chicken(395373) ATP citrate lyase
  • Horse(100053195) ATP citrate lyase
  • cow(511135) ATP citrate lyase
  • domestic cat(100422779) ATP citrate lyase
  • dog(607852) ATP citrate lyase
  • naked mole-rat(101700349) ATP citrate lyase
  • domestic guinea pig(100714933) ATP citrate lyase
  • sheep(654404) ATP citrate lyase

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Antibodies

Product Number
Opis
Reaktywność gatunkowa
Zastosowanie
HPA028758
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
HPA022434
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
HPA022953
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunofluorescence
immunohistochemistry
western blot
HPA022959
Anti-ACLY antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
western blot
SAB5702322
Przeciwciało anty-ACLY, klon 8A0V0, królicze monoklonalne, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
immunoprecipitation (IP)
western blot

Proteins

Product Number
Opis
Gatunek
SRP0288
ATP Citrate Lyase Active human, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Product Number
Opis
Gatunek
EMU005061
MISSION® esiRNA, targeting mouse Acly,
Gatunek
mouse
EHU081921
MISSION® esiRNA, targeting human ACLY,
Gatunek
human