ACLY
ATP citrate lyase
Synonimy:
ACL, ATPCL, CLATP
Gatunek:
Human ACLY (47), Mouse Acly (104112), Rat Acly (24159), chicken ACLY (395373), Horse ACLY (100053195), cow ACLY (511135), domestic cat ACLY (100422779), dog ACLY (607852), naked mole-rat Acly (101700349), domestic guinea pig Acly (100714933)
Identyfikator UniProtKB:
Identyfikator genu:
- Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
- Mouse(104112) ATP citrate lyase
- Rat(24159) ATP citrate lyase
- chicken(395373) ATP citrate lyase
- Horse(100053195) ATP citrate lyase
- cow(511135) ATP citrate lyase
- domestic cat(100422779) ATP citrate lyase
- dog(607852) ATP citrate lyase
- naked mole-rat(101700349) ATP citrate lyase
- domestic guinea pig(100714933) ATP citrate lyase
- sheep(654404) ATP citrate lyase
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Antibodies
Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ATP-Citrate Lyase antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
western blot
western blot
Anti-phospho-ATP-Citrate Lyase (pSer454) antibody produced in rabbit, affinity isolated antibody,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
ELISA
immunohistochemistry
western blot
immunohistochemistry
western blot
Przeciwciało anty-ACLY, klon 5F8D11, clone 5F8D11, from mouse,
Reaktywność gatunkowa
human, monkey, mouse
Zastosowanie
ELISA
flow cytometry
immunofluorescence
immunohistochemistry
western blot
flow cytometry
immunofluorescence
immunohistochemistry
western blot
Przeciwciało przeciw syntazie cytrynianu ATP/ACLY, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
bovine, human, mouse, porcine, rat, sheep
Zastosowanie
immunohistochemistry
western blot
western blot
Anti-ACLY Antibody, clone 1B16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
affinity binding assay
immunocytochemistry
immunohistochemistry
western blot
immunocytochemistry
immunohistochemistry
western blot
Proteins
Numer produktu
Opis
Gatunek
ATP Citrate Lyase Active human, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
Gatunek
human