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ACLY

ATP citrate lyase

Synonimy:
ACL, ATPCL, CLATP
Gatunek:
Identyfikator UniProtKB:
Identyfikator genu:
  • Human(47) Summary: ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  • Mouse(104112) ATP citrate lyase
  • Rat(24159) ATP citrate lyase
  • chicken(395373) ATP citrate lyase
  • Horse(100053195) ATP citrate lyase
  • cow(511135) ATP citrate lyase
  • domestic cat(100422779) ATP citrate lyase
  • dog(607852) ATP citrate lyase
  • naked mole-rat(101700349) ATP citrate lyase
  • domestic guinea pig(100714933) ATP citrate lyase
  • sheep(654404) ATP citrate lyase

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Antibodies

Numer produktu
Opis
Reaktywność gatunkowa
Zastosowanie
Anti-ACLY Antibody, clone 8A0V0, Rabbit Monoclonal, ,
Reaktywność gatunkowa
human, rat
Zastosowanie
immunofluorescence
immunoprecipitation (IP)

western blot
Anti-ACLY Antibody, clone 1B16 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
affinity binding assay
immunocytochemistry

immunohistochemistry

western blot
Anti-ACLY, clone 5F8D11 Antibody, clone 5F8D11, from mouse,
Reaktywność gatunkowa
human, monkey, mouse
Zastosowanie
ELISA
flow cytometry

immunofluorescence

immunohistochemistry

western blot
Anti-Phospho-ACLY-S455 antibody produced in rabbit, ,
Reaktywność gatunkowa
human, mouse, rat
Zastosowanie
immunohistochemistry
immunoprecipitation (IP)

western blot
Anti-ATP-citrate synthase/ACLY Antibody, from rabbit, purified by affinity chromatography,
Reaktywność gatunkowa
bovine, human, mouse, porcine, rat, sheep
Zastosowanie
immunohistochemistry
western blot

Proteins

Numer produktu
Opis
Gatunek
ATP Citrate Lyase Active human, recombinant, expressed in baculovirus, ≥90% (SDS-PAGE),
Gatunek
human

esiRNA

Numer produktu
Opis
Gatunek
MISSION® esiRNA, targeting human ACLY,
Gatunek
human
MISSION® esiRNA, targeting mouse Acly,
Gatunek
mouse