1303501

Halothane

United States Pharmacopeia (USP) Reference Standard

• Synonym(s): 2-Bromo-2-chloro-1,1,1-trifluoroethane, Halothane
• Linear Formula: BrCH(Cl)CF₃
• CAS Number: 151-67-7
• Molecular Weight: 197.38
• Beilstein: 1736947
• MDL number: MFCD00009602
• UNSPSC Code: 41116107
• PubChem Substance ID: 329749984
• NACRES: NA.24

Properties

• grade: pharmaceutical primary standard
• vapor pressure: 4.5 psi ( 20 °C)
• API family: halothane
• manufacturer/tradename: USP
• refractive index: n20/D 1.369 (lit.)
• bp: 50.2 °C (lit.)
• density: 1.872 g/mL at 25 °C (lit.)
• application(s): pharmaceutical (small molecule)
• format: neat
• storage temp.: 2-8°C
• SMILES string: FC(F)(F)C(Cl)Br
• InChI: 1S/C2HBrClF3/c3-1(4)2(5,6)7/h1H
• InChI key: BCQZXOMGPXTTIC-UHFFFAOYSA-N
• Gene Information: human ... GABRA1(2554) , GABRA2(2555) , GABRA3(2556) , GABRA4(2557) , GABRA5(2558) , GABRA6(2559) , GABRB1(2560) , GABRB2(2561) , GABRB3(2562) , GABRD(2563) , GABRE(2564) , GABRG1(2565) , GABRG2(2566) , GABRG3(2567) , GABRP(2568) , GABRQ(55879) , GLRA1(2741) , GLRB(2743) , KCNK10(54207) , KCNK18(338567) , KCNK2(3776) , KCNK3(3777) , KCNK9(51305)

Description

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Halothane USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

Biochem/physiol Actions

2-Bromo-2-chloro-1,1,1-trifluoroethane is an inhalation anesthetic. In an effect believed to be independent of anesthesia, halothane inhibits the synthesis of 5-hydroxytryptamine in brain tissue, probably at the tryptophan hydroxylase step.

Analysis Note

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

Other Notes

Sales restrictions may apply.

Safety Information

• Pictograms: GHS05,GHS07,GHS08
• Signal Word: Danger
• Hazard Statements: H315 - H318 - H335 - H360
• Precautionary Statements: P201 - P280 - P305 + P351 + P338 + P310 - P308 + P313
• Hazard Classifications: Eye Dam. 1 - Repr. 1B - Skin Irrit. 2 - STOT SE 3
• Target Organs: Respiratory system
• Storage Class Code: 6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3