H8627
Hydroxyurea
98% (elemental analysis), powder, RNR inhibitor
Synonym(s):
Hydroxycarbamide
About This Item
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product name
Hydroxyurea, 98%, powder
Quality Level
Assay
98%
form
powder
color
white
solubility
H2O: 50 mg/mL
storage temp.
2-8°C
SMILES string
NC(=O)NO
InChI
1S/CH4N2O2/c2-1(4)3-5/h5H,(H3,2,3,4)
InChI key
VSNHCAURESNICA-UHFFFAOYSA-N
Gene Information
human ... CA1(759) , CA2(760) , CYP1A2(1544) , RRM1(6240) , RRM2(6241) , RRM2B(50484)
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General description
Application
- for cell cycle synchronization in MCF-7 human breast carcinoma cells, Schizosaccharomyces pombe, primary root of seedling
- as a drug for treating the parasite Leishmania mexicana in cell viability and cell cycle assay
- as an inhibitor in the cell adhesion and motility assay in Caki control and CD9 knockdown cells
Biochem/physiol Actions
Features and Benefits
Signal Word
Danger
Hazard Statements
Precautionary Statements
Hazard Classifications
Muta. 1B - Repr. 2
Storage Class Code
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
WGK
WGK 3
Flash Point(F)
Not applicable
Flash Point(C)
Not applicable
Personal Protective Equipment
Certificates of Analysis (COA)
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n proliferating cells, the cell cycle consists of four phases. Gap 1 (G1) is the interval between mitosis and DNA replication that is characterized by cell growth. Replication of DNA occurs during the synthesis (S) phase, which is followed by a second gap phase (G2) during which growth and preparation for cell division occurs. Together, these three stages comprise the interphase phase of the cell cycle. Interphase is followed by the mitotic (M) phase.
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