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Merck
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Key Documents

SRP6107

Sigma-Aldrich

SOD-A from bacteria

recombinant, expressed in E. coli, ≥95% (SDS-PAGE)

Sinónimos:

MnSOD, SOD2, Superoxide dismutase, manganese

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About This Item

UNSPSC Code:
12352200
NACRES:
NA.32

biological source

bacterial

recombinant

expressed in E. coli

assay

≥95% (SDS-PAGE)

form

liquid

mol wt

25.2 kDa (226 aa, 1-206 aa + His Tag)

packaging

pkg of 100 μg

UniProt accession no.

P00448

shipped in

dry ice

storage temp.

−70°C

Gene Information

Escherichia coli K12 ... sodA(948403)

General description

Manganese-type superoxide dismutase, also known as SodA, is a member of the iron/manganese superoxide dismutase family.

Biochem/physiol Actions

Superoxide dismutase (SodA) destroys radicals which are normally produced within the cells and which are toxic to biological systems. It works by catalyzing the dismutation of the superoxide radical O2- to O2 and H2O2, which are then metabolized to H2O and O2 by catalase and glutathione peroxidase.

Physical form

1 mg/mL solution in 20 mM Tris-HCl (pH 8.0) containing 1 mM DTT, 0.1 M NaCl and 10% glycerol.

Preparation Note

Centrifuge the vial prior to opening.

Other Notes

MGSSHHHHHH SSGLVPRGSH MSYTLPSLPY AYDALEPHFD KQTMEIHHTK HHQTYVNNAN AALESLPEFA NLPVEELITK LDQLPADKKT VLRNNAGGHA NHSLFWKGLK KGTTLQGDLK AAIERDFGSV DNFKAEFEKA AASRFGSGWA WLVLKGDKLA VVSTANQDSP LMGEAISGAS GFPIMGLDVW EHAYYLKFQN RRPDYIKEFW NVVNWDEAAA RFAAKK

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

Certificados de análisis (COA)

Busque Certificados de análisis (COA) introduciendo el número de lote del producto. Los números de lote se encuentran en la etiqueta del producto después de las palabras «Lot» o «Batch»

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A manganese-rich environment supports superoxide dismutase activity in a Lyme disease pathogen, Borrelia burgdorferi.
Aguirre JD
The Journal of Biological Chemistry, 288(12), 8468-8478 (2013)
[Oxygen radicals-superoxide dismutase system and reproduction medicine].
Ishikawa M
Nihon Sanka Fujinka Gakkai Zasshi, 45(8), 842-848 (1993)
Oxidants, antioxidants and carcinogenesis.
Ray G and Husain SA
Indian Journal of Experimental Biology, 40(11), 1213-1232 (2002)
Carmen Cerchia et al.
Antioxidants (Basel, Switzerland), 11(4) (2022-04-24)
The microaerophile Streptococcus mutans, the main microaerophile responsible for the development of dental plaque, has a single cambialistic superoxide dismutase (SmSOD) for its protection against reactive oxygen species. In order to discover novel inhibitors of SmSOD, possibly interfering with the

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