362824

Acetyltrimethylsilane

97%

• Sinónimos: 1-(Trimethylsilyl)ethanone
• Fórmula lineal: (CH₃)₃SiCOCH₃
• Número de CAS: 13411-48-8
• Peso molecular: 116.23
• Beilstein/REAXYS Number: 2071361
• MDL number: MFCD00134244
• UNSPSC Code: 12352103
• PubChem Substance ID: 24862334
• NACRES: NA.22

Propiedades

• assay: 97%
• refractive index: n20/D 1.411 (lit.)
• density: 0.811 g/mL at 25 °C (lit.)
• storage temp.: 2-8°C
• SMILES string: CC(=O)[Si](C)(C)C
• InChI: 1S/C5H12OSi/c1-5(6)7(2,3)4/h1-4H3
• InChI key: REDWSDBFBCDPNI-UHFFFAOYSA-N

Descripción

General description

Acetyltrimethylsilane is an organosilicon compound that is commonly used as a protective agent for alcohols and amines in organic synthesis. It is also used as a reagent in various reactions, which includes trimethylsilylation, condensation, carbon-carbon bond formation, and reductive amination reactions.

Application

Acetyltrimethylsilane can be used as a reagent in the synthesis of dihydrophenanthrenes via a C-C insertion reaction. It is also used as a source of carbanion in the synthesis of unsymmetrical biaryls by carbanion-induced ring transformation of 2H-pyran-2-ones under mild basic conditions.

Información de seguridad

• pictograms: GHS02,GHS07
• signalword: Danger
• hcodes: H225,H315,H319,H335
• pcodes: P210 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Flam. Liq. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 46.4 °F - closed cup
• flash_point_c: 8 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter