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Merck

HDAC6

histone deacetylase 6

Sinónimos:
HD6
Especie:
Human HDAC6 (10013), Mouse Hdac6 (15185), Rat Hdac6 (84581), Zebrafish hdac6 (565482), domestic cat HDAC6 (101084086), cow HDAC6 (513602), dog HDAC6 (480907), fruit fly HDAC6 (32461), domestic guinea pig Hdac6 (100717988), naked mole-rat Hdac6 (101708442)
ID UniProtKB:
Q9UBN7, O94975, Q6NT75, Q7L3E5, Q96CY0
ID del gen:
  • Human(10013) Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It contains an internal duplication of two catalytic domains which appear to function independently of each other. This protein possesses histone deacetylase activity and represses transcription. [provided by RefSeq, Jul 2008]
  • Mouse(15185) histone deacetylase 6
  • Rat(84581) histone deacetylase 6
  • Zebrafish(565482) histone deacetylase 6
  • domestic cat(101084086) histone deacetylase 6
  • cow(513602) histone deacetylase 6
  • dog(480907) histone deacetylase 6
  • fruit fly(32461) CG6170 gene product from transcript CG6170-RA
  • domestic guinea pig(100717988) histone deacetylase 6
  • naked mole-rat(101708442) histone deacetylase 6
  • sheep(101109245) histone deacetylase 6

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Antibodies

Referencia del producto
Descripción
Reactividad de especies
Aplicación
HPA003714
Anti-HDAC6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab1,
Reactividad de especies
human
Aplicación
immunohistochemistry
SAB4500011
Anti-HDAC6 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunofluorescence
immunohistochemistry
western blot
SAB4301481
Anti-phospho-HDAC6 (pSer22) antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
western blot
SAB4500012
Anti-HDAC6 antibody produced in rabbit, affinity isolated antibody,
Reactividad de especies
human, mouse
Aplicación
ELISA
immunohistochemistry
western blot
HPA026321
Anti-HDAC6 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution, Ab2,
Reactividad de especies
human
Aplicación
immunofluorescence
immunohistochemistry

Small Molecule - Inhibitor

Referencia del producto
Descripción
Especie
SML0061
SAHA, ≥98% (HPLC),
Especie
human
T8552
Trichostatin A, ≥98% (HPLC), from Streptomyces sp.,
Especie
human, mouse, rat
SML1175
Romidepsin, ≥98% (HPLC),
Especie
human
C0621
CI−994, ≥98% (HPLC), powder,
Especie
human

Proteins

Referencia del producto
Descripción
Especie
SRP0108
HDAC-6 human, recombinant, expressed in baculovirus infected insect cells, ≥80% (SDS-PAGE),
Especie
human
SRP0310
HDAC6 H216A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥75% (SDS-PAGE),
Especie
human
SRP0311
HDAC6 H611A human, recombinant, expressed in baculovirus infected Sf9 cells, ≥79% (SDS-PAGE),
Especie
human

esiRNA

Referencia del producto
Descripción
Especie
EMU055151
MISSION® esiRNA, targeting mouse Hdac6,
Especie
mouse
EHU054851
MISSION® esiRNA, targeting human HDAC6,
Especie
human