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Merck

MST1R

macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

Synonyms:
CD136, CDw136, PTK8, RON
Species:
UniProtKB ID:
Gene ID:
  • Human(4486) Summary: This gene encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity. The mature form of this protein is a heterodimer of disulfide-linked alpha and beta subunits, generated by proteolytic cleavage of a single-chain precursor. The beta subunit undergoes tyrosine phosphorylation upon stimulation by MSP. This protein is expressed on the ciliated epithelia of the mucociliary transport apparatus of the lung, and together with MSP, thought to be involved in host defense. Alternatively spliced transcript variants encoding different isoforms with different structural and biochemical properties have been described (PMID:8816464). [provided by RefSeq, Oct 2011]
  • Mouse(19882) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • Rat(300999) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • chicken(427573) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • domestic cat(101089993) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • cow(525504) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • Horse(100062492) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • dog(444854) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • sheep(101116433) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • naked mole-rat(101720807) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)
  • domestic guinea pig(100732415) macrophage stimulating 1 receptor (c-met-related tyrosine kinase)

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ELISA

Product Number
Description
Species
Human MSP Receptor ELISA, for serum, plasma and cell culture supernatants,
Species
human

Antibodies

Product Number
Description
Species Reactivity
Application
Monoclonal Anti-MST1R antibody produced in mouse, clone 4E2, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-MST1R antibody produced in mouse, clone 1H8, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
Monoclonal Anti-MST1R antibody produced in mouse, Prestige Antibodies® Powered by Atlas Antibodies, clone CL0463, purified immunoglobulin, buffered aqueous glycerol solution,
Species Reactivity
human
Application
western blot
Anti-phospho-CD136/RON (pSer1394) antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
western blot
ANTI-MST1R antibody produced in mouse, clone 2F3, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA

Proteins

Product Number
Description
Species
RON (983-end), active, GST tagged human, PRECISIO® Kinase, recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE), buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting human MST1R,
Species
human
MISSION® esiRNA, targeting mouse Mst1r,
Species
mouse