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914134

Sigma-Aldrich

5-(Biotinamido)pentylamine TFA Salt

≥95%

Synonym(s):

N-(5-Aminopentyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pent, Biotin cadaverine TFA, Biotin-DAPe TFA

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About This Item

Empirical Formula (Hill Notation):
C15H28N4O2S · xC2HF3O2
Molecular Weight:
328.47 (free base basis)
MDL number:
MFCD03452814
UNSPSC Code:
12352116
NACRES:
NA.22

Quality Level

100

Assay

≥95%

form

powder

mp

116-121 °C

storage temp.

2-8°C

SMILES string

FC(F)(F)C(=O)O.S1[C@H]([C@H]2NC(=O)N[C@H]2C1)CCCCC(=O)NCCCCCN

InChI key

QWKKJNXOPDNIEU-RGESYUBESA-N

Application

5-(Biotinamido)pentylamine TFA Salt is a versatile biotinylated linker that can be incorporated into chemical tools via its terminal amino group. Labeling materials or proteins with biotin provides a means to enrich and capture targets from biological systems.

Automate your Biotin tagging with Synple Automated Synthesis Platform (SYNPLE-SC002)

Other Notes

Site-selective conversion of azido groups at carbonyl α-positions into oxime groups leading triazide to a triple click conjugation scaffold

Convergent synthesis of trifunctional molecules by three sequential azido-type-selective cycloadditions

Locked by Design: A Conformationally Constrained Transglutaminase Tag Enables Efficient Site-Specific Conjugation

Synthesis of Novel Phosphonic-Type Activity-Based Probes for Neutrophil Serine Proteases and Their Application in Spleen Lysates of Different Organisms

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Description
Pricing

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Coenzyme A analogues are synthesized in a one-pot preparation by biotransformation of pantothenate thioesters through the simultaneous use of three CoA biosynthetic enzymes, followed by aminolysis.
Taiki Yokoi et al.
Chemical communications (Cambridge, England), 55(13), 1891-1894 (2018-12-21)
This paper reports the selective conversion of alkyl azido groups at the carbonyl α-position into oximes through β-elimination of dinitrogen, followed by transoximation. With this method and diazo conversion, a triazido molecule was transformed into a triple click conjugation scaffold
Collette S Guy et al.
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