V900919

Amphotericin B from Streptomyces sp.

suitable for cell culture, Vetec^™, BioReagent

• 동의어(들): Amphotericin B from Streptomyces sp., Fungizone
• 실험식(Hill 표기법): C₄₇H₇₃NO₁₇
• CAS Number: 1397-89-3
• Molecular Weight: 924.08
• Beilstein: 78342
• EC Number: 215-742-2
• MDL number: MFCD00877763
• UNSPSC 코드: 12352207
• PubChem Substance ID: 329830225

속성

• 제품명: Amphotericin B from Streptomyces sp., Vetec^™, reagent grade, BioReagent, suitable for cell culture, ~80%
• Grade: reagent grade
• Quality Level: 100
• 제품 라인: BioReagent; Vetec^™
• 분석: ~80%
• 기술: cell culture | mammalian: suitable
• 항생제 활성 스펙트럼: fungi; yeast
• 동작 모드: cell membrane | interferes
• 저장 온도: 2-8°C
• SMILES string: C[C@H]1O[C@@H](O[C@@H]2C[C@@H]3O[C@](O)(C[C@@H](O)C[C@@H](O)[C@H](O)CC[C@@H](O)C[C@@H](O)CC(=O)O[C@@H](C)[C@H](C)[C@H](O)[C@@H](C)\C=C\C=C\C=C\C=C\C=C\C=C\C=C\2)C[C@H](O)[C@H]3C(O)=O)[C@@H](O)[C@@H](N)[C@@H]1O
• InChI: 1S/C47H73NO17/c1-27-17-15-13-11-9-7-5-6-8-10-12-14-16-18-34(64-46-44(58)41(48)43(57)30(4)63-46)24-38-40(45(59)60)37(54)26-47(61,65-38)25-33(51)22-36(53)35(52)20-19-31(49)21-32(50)23-39(55)62-29(3)28(2)42(27)56/h5-18,27-38,40-44,46,49-54,56-58,61H,19-26,48H2,1-4H3,(H,59,60)/b6-5+,9-7+,10-8+,13-11+,14-12+,17-15+,18-16+/t27-,28-,29-,30+,31+,32+,33-,34-,35+,36+,37-,38-,40+,41-,42+,43+,44-,46-,47+/m0/s1
• InChI key: APKFDSVGJQXUKY-INPOYWNPSA-N

설명

생화학적/생리학적 작용

Amphotericin B binds to sterols, forming pores in the membrane, and causing small molecules to leak out. The product is most effective against fungi and yeast.

Amphotericin B is used for primary treatment of acute invasive fungal infections, such as aspergillosis.

법적 정보

Vetec is a trademark of Merck KGaA, Darmstadt, Germany

안전성 정보

• 픽토그램: GHS08
• 신호어: Danger
• 유해 및 위험 성명서: H372
• 예방조치 성명서: P260 - P264 - P270 - P314 - P501
• Hazard Classifications: STOT RE 1
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable