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Key Documents

1500218

USP

Paroxetine hydrochloride

United States Pharmacopeia (USP) Reference Standard

동의어(들):

Paroxetine hydrochloride hemihydrate, (3S-trans)-3-[(1,3-Benzodioxol-5-yloxy)methyl]-4-(4-fluorophenyl)piperidine hydrochloride hemihydrate

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About This Item

실험식(Hill 표기법):
C19H20FNO3 · HCl · .5 H2O
CAS Number:
Molecular Weight:
374.83
MDL number:
UNSPSC 코드:
41116107
PubChem Substance ID:
NACRES:
NA.24

Grade

pharmaceutical primary standard

API family

paroxetine

제조업체/상표

USP

응용 분야

pharmaceutical (small molecule)

형식

neat

SMILES string

O.Cl[H].Fc1ccc(cc1)[C@@H]2CCNC[C@H]2COc3ccc4OCOc4c3

InChI

1S/C19H20FNO3.ClH.H2O/c20-15-3-1-13(2-4-15)17-7-8-21-10-14(17)11-22-16-5-6-18-19(9-16)24-12-23-18;;/h1-6,9,14,17,21H,7-8,10-12H2;1H;1H2/t14-,17-;;/m0../s1

InChI key

QRQSGFFISBKLMZ-YHOFXEKLSA-N

유전자 정보

human ... SLC6A4(6532)

유사한 제품을 찾으십니까? 방문 제품 비교 안내

일반 설명

Paroxetine hydrochloride is a phenylpiperidine derivative which is selective serotonin reuptake inhibitor. The protein binding ability is high. It has 2 forms, non-hygroscopic hemihydrate and hygroscopic anhydrate. This drug is seen useful in treating premature ejaculation in men.
This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Paroxetine hydrochloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia.

생화학적/생리학적 작용

Paroxetine hydrochloride hemihydrate is one of the most potent and selective of the selective serotonin reuptake inhibitors (SSRI); antidepressant

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

관련 제품

제품 번호
설명
가격

픽토그램

Exclamation markEnvironment

신호어

Warning

유해 및 위험 성명서

Hazard Classifications

Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Sens. 1 - STOT SE 3

표적 기관

Respiratory system

Storage Class Code

11 - Combustible Solids

WGK

WGK 3

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable


시험 성적서(COA)

제품의 로트/배치 번호를 입력하여 시험 성적서(COA)을 검색하십시오. 로트 및 배치 번호는 제품 라벨에 있는 ‘로트’ 또는 ‘배치’라는 용어 뒤에서 찾을 수 있습니다.

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문서 라이브러리 방문

Perinatal outcome following third trimester exposure to paroxetine.
Costei, Adriana Moldovan, et al.
Archives of Pediatrics & Adolescent Medicine, 156.11, 1129-1132 (2002)
C G McMahon et al.
International journal of impotence research, 11(5), 241-245 (1999-12-20)
To evaluate the efficacy of chronic and 'on demand' administration of paroxetine hydrochloride in the drug treatment of premature ejaculation (PE). Ninety-four normally potent men, aged 18-61 y (mean 39 y) with premature ejaculation were treated between January 1996 and
Solid-state forms of paroxetine hydrochloride.
Buxton, P. Christopher, Ian R. Lynch, and John M. Roe.
International Journal of Pharmaceutics, 42.1, 135-143 (1988)
E Di Girolamo et al.
Journal of the American College of Cardiology, 33(5), 1227-1230 (1999-04-08)
The purpose of the study was to determine whether the well tolerated serotonin reuptake inhibitor paroxetine hydrochloride could prevent vasovagal syncope in patients resistant to or intolerant of previous traditional therapies. Serotonergic mechanisms play a major role in the processes
Puja Panwar Hazari et al.
ChemMedChem, 9(2), 337-349 (2014-01-01)
A novel SiX-dipropargyl glycerol scaffold (X: H, F, or (18) F) was developed as a versatile prosthetic group that provides technical advantages for the preparation of dimeric radioligands based on silicon fluoride acceptor pre- or post-labeling with fluorine-18. Rapid conjugation

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