1065210

Berberine chloride

United States Pharmacopeia (USP) Reference Standard

• 동의어(들): Berberine chloride form, Natural Yellow 18
• 실험식(Hill 표기법): C₂₀H₁₈ClNO₄
• CAS Number: 633-65-8
• Molecular Weight: 371.81
• 색상 지수 번호: 75160
• Beilstein: 3836585
• MDL number: MFCD00011939
• UNSPSC 코드: 41116107
• PubChem Substance ID: 329748923
• NACRES: NA.24

속성

• Grade: pharmaceutical primary standard
• API family: berberine
• 제조업체/상표: USP
• 응용 분야: pharmaceutical (small molecule)
• 형식: neat
• SMILES string: COC1=C(C=[N+](CCC2=C3C=C4C(OCO4)=C2)C3=C5)C5=CC=C1OC.[Cl-]
• InChI: 1S/C20H18NO4.ClH/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2;/h3-4,7-10H,5-6,11H2,1-2H3;1H/q+1;/p-1
• InChI key: VKJGBAJNNALVAV-UHFFFAOYSA-M

설명

일반 설명

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.
For further information and support please go to the website of the issuing Pharmacopoeia.

애플리케이션

Berberine chloride USP reference standard, intended for use in specified quality tests and assays as specified in the USP compendia. Also, for use with USP monographs such as:

• Coptis Species Rhizome
• Coptis Species Rhizome Dry Extract
• Coptis Species Rhizome Powder
• Goldenseal
• Indian Barberry Stem
• Indian Barberry Stem Dry Extract
• Indian Barberry Stem Powder

Fluorescent stain for heparin in mast cells

생화학적/생리학적 작용

An alkaloid with weak antibiotic properties. Substrate for MDR efflux pumps. Antimicrobial activities of berberine is potentiated by the MDR inhibitor 5´-methoxyhydnocarpin (5´-MHC). Berberine upregulates the expression of Pgp in hepatoma cells. Treatment with berberine potentially results in the reduced accumulation of chemotherapeutic drugs.

분석 메모

These products are for test and assay use only. They are not meant for administration to humans or animals and cannot be used to diagnose, treat, or cure diseases of any kind.  ​

기타 정보

Sales restrictions may apply.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable