추천 제품
설명
non-ionic
제품 라인
BioXtra
불순물
<0.0005% Phosphorus (P)
무기 잔류물
<1.0%
CMC
0.018 mM
전이 온도
cloud point 94.3 °C
음이온 미량물
chloride (Cl-): <0.05%
sulfate (SO42-): <0.6%
양이온 미량물
Al: <0.0005%
Ca: <0.0005%
Cu: <0.0005%
Fe: <0.001%
K: <0.005%
Mg: <0.0005%
NH4+: <0.05%
Na: <0.5%
Pb: <0.001%
Zn: <0.0005%
SMILES string
[H]C([H])=O.OCCO.CC(C)(C)CC(C)(C)c1ccc(O)cc1
InChI
1S/C14H22O.C2H6O2.CH2O/c1-13(2,3)10-14(4,5)11-6-8-12(15)9-7-11;3-1-2-4;1-2/h6-9,15H,10H2,1-5H3;3-4H,1-2H2;1H2
InChI key
GWJOFBXSBDVUMH-UHFFFAOYSA-N
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일반 설명
A nonionic liquid polymer of the alkyl aryl polyether alcohol type. Used as a surfactant.
Tyloxapol is a biocompatible surfactant
애플리케이션
Tyloxapol has been used in a study to assess the enhanced pulmonary absorption of recombinant human insulin. It has also been used in a study to investigate the metabolic pathways promoting intrahepatic fatty acid accumulation in methionine and choline deficiency.
신호어
Warning
유해 및 위험 성명서
Hazard Classifications
Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
표적 기관
Respiratory system
Storage Class Code
10 - Combustible liquids
WGK
WGK 2
Flash Point (°F)
235.4 °F - closed cup
Flash Point (°C)
113 °C - closed cup
개인 보호 장비
Eyeshields, Gloves, type ABEK (EN14387) respirator filter
이미 열람한 고객
Martina Theresa Hackl et al.
Nature communications, 10(1), 2717-2717 (2019-06-22)
Hepatic steatosis develops when lipid influx and production exceed the liver's ability to utilize/export triglycerides. Obesity promotes steatosis and is characterized by leptin resistance. A role of leptin in hepatic lipid handling is highlighted by the observation that recombinant leptin
David P Macfarlane et al.
American journal of physiology. Endocrinology and metabolism, 300(2), E402-E409 (2010-12-02)
The pathological mechanisms that distinguish simple steatosis from steatohepatitis (or NASH, with consequent risk of cirrhosis and hepatocellular cancer) remain incompletely defined. Whereas both a methionine- and choline-deficient diet (MCDD) and a choline-deficient diet (CDD) lead to hepatic triglyceride accumulation
Formulation of Tyloxapol niosomes for encapsulation, stabilization and dissolution of anti-tubercular drugs
Mehta, S. and N. Jindal
Colloids and Surfaces. B, Biointerfaces, 434?441-434?441 (2013)
Jianheng Zheng et al.
Die Pharmazie, 67(5), 448-451 (2012-07-07)
Natural pulmonary surfactant (PS) and its artificial substitute phospholipid hexadecanol tyloxapol (PHT) are effective absorption enhancers on promoting recombinant human insulin (Rh-ins) absorption in vivo, but the in vitro efficacy and underlying mechanism remains unclear. In the current study, the
Aki Uchida et al.
Frontiers in physiology, 3, 26-26 (2012-03-01)
Obesity results in abnormally high levels of triglyceride (TG) storage in tissues such as liver, heart, and muscle, which disrupts their normal functions. Recently, we found that lean mice challenged with high levels of dietary fat store TGs in cytoplasmic
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