SRP8010

GPX1 human

recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE)

• 동의어(들): Cellular glutathione peroxidase, Death receptor 6, GSHPx-1, Glutathione peroxidase 1
• CAS Number: 1451392-36-1
• UNSPSC 코드: 12352200
• NACRES: NA.32

속성

• 생물학적 소스: human
• 재조합: expressed in E. coli
• 태그: His tagged
• 분석: >90% (SDS-PAGE)
• 양식: lyophilized
• 분자량: ~25 kDa by SDS-PAGE
• 포장: pkg of 10 μg
• 저장 조건: avoid repeated freeze/thaw cycles
• 불순물: <1 EU/μg endotoxin, tested
• 색상: white
• UniProt 수납 번호: P07203
• 배송 상태: wet ice
• 저장 온도: −20°C
• 유전자 정보: human ... GPX1(2876)

설명

일반 설명

GPX1 (glutathione peroxidase 1) is a selenoprotein and the gene is mapped to human chromosome 3p21.3. It is present in the cytoplasm and is widely expressed.

생화학적/생리학적 작용

GPX1 (glutathione peroxidase 1) is responsible for scavenging free radicals and derivatives. GPXs reduces lipid hydroperoxides to the corresponding alcohols as well as free hydrogen peroxide to water. Mutations in the GPX1 gene are associated with nonalcoholic fatty liver disease (NAFLD) susceptibility. Mutation in GPX1 at C594T is linked with oxidative stress-associated disorders, including prostate cancer and bladder cancer.

물리적 형태

Lyophilized from 55 mM TRIS-HCl, pH 8.2, containing 150 mM NaCl, 1 mM DTT.

재구성

Reconstitute with 100 μL deionized water.

기타 정보

Human GPX1 (aa 1-201) is fused at the C-terminus to a His-tag.

안전성 정보

• Storage Class Code: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable