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Merck
모든 사진(2)

Key Documents

SRP0352

Sigma-Aldrich

TRKC active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥70% (SDS-PAGE)

동의어(들):

NT-3 Receptor, NTKR3, Neurotrophic Tyrosine Kinase Receptor, type 3

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모든 사진(2)

About This Item

CAS Number:
2122170-03-8
UNSPSC 코드:
12352200
NACRES:
NA.32

생물학적 소스

human

재조합

expressed in baculovirus infected Sf9 cells

분석

≥70% (SDS-PAGE)

형태

aqueous solution

분자량

68 kDa

포장

pkg of 10 μg

기술

activity assay: suitable
inhibition assay: suitable

NCBI 수납 번호

NM_002530

UniProt 수납 번호

Q16288

배송 상태

dry ice

저장 온도

−70°C

유전자 정보

human ... NTRK3(4916)

일반 설명

Human TRKC, also known as NTKR3 (Neurotrophic Tyrosine Kinase Receptor, type 3) or NT-3 Receptor, (GenBank Accession No. NM_002530), amino acids 456-825 (end) with N-terminal GST-tag, MW=68kDa, expressed in Sf9 cells via a Baculovirus expression system.

애플리케이션

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Storage Class Code

12 - Non Combustible Liquids

WGK

WGK 1

Flash Point (°F)

Not applicable

Flash Point (°C)

Not applicable

시험 성적서(COA)

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문서 라이브러리 방문

L Tessarollo et al.
Development (Cambridge, England), 118(2), 463-475 (1993-06-01)
The Trk family of tyrosine kinases encodes receptors for nerve growth factor-related neurotrophins. Here we present a developmental expression study of trkC, which encodes a receptor for neurotrophin-3 (NT-3). Like the related genes, trk and trkB, trkC is expressed primarily
L M McGregor et al.
Genomics, 22(2), 267-272 (1994-07-15)
TrkC is a receptor tyrosine kinase that is activated by neurotrophin-3, a factor important in the development of certain areas of the central nervous system. We have cloned and sequenced the human trkC cDNA and found that the predicted amino
F Lamballe et al.
Cell, 66(5), 967-979 (1991-09-06)
We report the isolation and molecular characterization of trkC, a new member of the trk family of tyrosine protein kinase genes. trkC is preferentially expressed in the brain. In situ hybridization studies revealed trkC transcripts in the hippocampus, cerebral cortex
Ke Zhang et al.
Stem cell reviews, 10(4), 612-625 (2014-05-03)
In the past decades, mesenchymal stem cells (MSCs) as a promising cell candidate have received the most attention in the treatment of spinal cord injury (SCI). However, due to the low survival rate and low neural differentiation rate, the grafted
Oswald Steward et al.
The Journal of neuroscience : the official journal of the Society for Neuroscience, 34(42), 14013-14021 (2014-10-17)
We reported previously the formation of ectopic colonies in widespread areas of the nervous system after transplantation of fetal neural stem cells (NSCs) into spinal cord transection sites. Here, we characterize the incidence, distribution, and cellular composition of the colonies.
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