SML2906

ERGi-USU

≥98% (HPLC)

• 동의어(들): 1-[2-(2-Thiazolyl)diazenyl]-2-naphthalenol, 1-[2-Thiazolylazo]-2-naphthol, NSC139021, TAN
• 실험식(Hill 표기법): C₁₃H₉N₃OS
• CAS Number: 1147-56-4
• Molecular Weight: 255.30
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: faint brown to dark red
• solubility: DMSO: 2 mg/mL, clear
• 저장 온도: −20°C
• InChI: 1S/C13H9N3OS/c17-11-6-5-9-3-1-2-4-10(9)12(11)15-16-13-14-7-8-18-13/h1-8,17H
• InChI key: IOMXCGDXEUDZAK-UHFFFAOYSA-N

설명

생화학적/생리학적 작용

ERGi-USU is a selective and potent inhibitor of growth of ERG positive cancer cell lines, while spearing normal prostate or endothelial cells. It potently inhibits growth of ERG positive VCaP xenografts in mice. ERGi-USU is a potent and selective ligand of the ribosomal atypical kinase RIOK2 (right open reading frame (RIO) kinase 2) that induces ribosomal stress.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3