SML1312

Mubritinib

≥98% (HPLC)

• 동의어(들): (E)-4-((4-(4-(1H-1,2,3-triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole, 1-[4-[4-[[2-[(1E)-2-[4-(Trifluoromethyl)phenyl]ethenyl]-4-oxazolyl]methoxy]phenyl]butyl]-1H-1,2,3-triazole, CID 6444692, TAK 165, TAK-165
• 실험식(Hill 표기법): C₂₅H₂₃F₃N₄O₂
• CAS Number: 366017-09-6
• Molecular Weight: 468.47
• MDL number: MFCD09954135
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825777
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 5 mg/mL, clear (warmed)
• 저장 온도: 2-8°C
• SMILES string: FC(F)(F)C1=CC=C(/C=C/C2=NC(COC3=CC=C(C=C3)CCCCN4C=CN=N4)=CO2)C=C1
• InChI: 1S/C25H23F3N4O2/c26-25(27,28)21-9-4-20(5-10-21)8-13-24-30-22(18-34-24)17-33-23-11-6-19(7-12-23)3-1-2-15-32-16-14-29-31-32/h4-14,16,18H,1-3,15,17H2/b13-8+
• InChI key: ZTFBIUXIQYRUNT-MDWZMJQESA-N
• 유전자 정보: human ... ERBB2(2064)

설명

생화학적/생리학적 작용

Mubritinib (TAK-165) is a potent and selective inhibitor of ErbB-2 (HER2).

Mubritinib (TAK-165) is a potent and selective inhibitor of the human epidermal growth factor receptor 2 ErbB (HER2) tyrosine kinase. Mubritinib potently inhibits proliferation of cancer cell lines over- expressing ErbB2.

안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable