SML1087

Sumanirole maleate

≥98% (HPLC)

• 동의어(들): (5R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, (R)-5,6-Dihydro-5-(methylamino)-4H-imidazo[4,5,1-ij]quinolin-2(1H)-one maleate, CID 9818479 maleate, PNU-95,666 maleate
• 실험식(Hill 표기법): C₁₁H₁₃N₃O · C₄H₄O₄
• CAS Number: 179386-44-8
• Molecular Weight: 319.31
• MDL number: MFCD09832637
• UNSPSC 코드: 12352200
• PubChem Substance ID: 329825464
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 광학 활성: [α]/D -22 to -32°, c = 1 in H₂O
• 저장 조건: desiccated
• 색상: white to beige
• solubility: H₂O: 10 mg/mL, clear
• 저장 온도: −20°C
• SMILES string: O=C1N(C[C@H](NC)C2)C3=C2C=CC=C3N1.O=C(O)/C=C\C(O)=O
• InChI: 1S/C11H13N3O.C4H4O4/c1-12-8-5-7-3-2-4-9-10(7)14(6-8)11(15)13-9;5-3(6)1-2-4(7)8/h2-4,8,12H,5-6H2,1H3,(H,13,15);1-2H,(H,5,6)(H,7,8)/b;2-1-/t8-;/m1./s1
• InChI key: VOJRMYBBPKNLLI-ORHWHDKWSA-N

설명

애플리케이션

Sumanirole maleate has been used as a dopamine type 2 receptor (D2R) agonist to study its effects on spatial learning and memory in rats.

생화학적/생리학적 작용

Sumanirole is a highly selective and potent dopamine D2 receptor agonist that decreased plasma prolactin levels and depressed dopamine neuron firing rates in the substantia nigra pars compacta. Sumanirole potently stimulates locomotor activity in in animal models of Parkinson′s disease.

특징 및 장점

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안전성 정보

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable