SML0738

RORγ Activator 1b

≥98% (HPLC)

• 동의어(들): N-(4,6-Dimethyl-2-benzothiazolyl)-3-methyl-2-thiophenecarboxamide
• 실험식(Hill 표기법): C₁₅H₁₄N₂OS₂
• CAS Number: 875286-88-7
• Molecular Weight: 302.41
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• 분석: ≥98% (HPLC)
• 형태: powder
• 색상: white to beige
• solubility: DMSO: 20 mg/mL, clear
• 저장 온도: 2-8°C

설명

생화학적/생리학적 작용

RORγ Activator 1b binds to the retinoid-related orphan receptor RORγ and induces IL-17 reporter gene expression with an EC₅₀ of 0.1 μM. The compound RORγ Activator 1b enhances differentiation of CD4+ T cells to IL-17-secreting cells with a maximum effect of 220 percent of control at 3 μM.

안전성 정보

• 픽토그램: GHS07
• 신호어: Warning
• 유해 및 위험 성명서: H302
• 예방조치 성명서: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable