SML0617

A-804598

≥98% (HPLC)

• 동의어(들): N-Cyano-N′′-[(1S)-1-phenylethyl]-N′-5-quinolinyl-guanidine
• 실험식(Hill 표기법): C₁₉H₁₇N₅
• CAS Number: 1125758-85-1
• Molecular Weight: 315.37
• UNSPSC 코드: 12352200
• NACRES: NA.77

속성

• Quality Level: 100
• 분석: ≥98% (HPLC)
• 양식: powder
• 색상: white to beige
• solubility: DMSO: 10 mg/mL, clear
• 저장 온도: 2-8°C
• SMILES string: N(c2c3c(nccc3)ccc2)\C(=N/[C@@H](C)c1ccccc1)\NC#N
• InChI: 1S/C19H17N5/c1-14(15-7-3-2-4-8-15)23-19(22-13-20)24-18-11-5-10-17-16(18)9-6-12-21-17/h2-12,14H,1H3,(H2,22,23,24)/t14-/m0/s1
• InChI key: PQYCRDPLPKGSME-AWEZNQCLSA-N

설명

생화학적/생리학적 작용

A-804598 is a P2X7 selective, competitive antagonist.

A-804598 is a P2X7 selective, competitive antagonist. In competition assays, the IC₅₀s for human, rat and mouse channels are 11, 10 and 9 nM, respectively.

특징 및 장점

This compound is featured on the P2 Receptors: P2X Ion Channel Family page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

안전성 정보

• 픽토그램: GHS06
• 신호어: Danger
• 유해 및 위험 성명서: H301
• 예방조치 성명서: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Storage Class Code: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• WGK: WGK 3
• Flash Point (°F): Not applicable
• Flash Point (°C): Not applicable